Best for mood

386 options people report for mood, motivation and low mood, ranked by the share of users who say it improved — weighted by how many reports there are.

Weight loss Appetite Focus Energy Sleep Anxiety Mood Memory Performance Recovery Pain & inflammation Digestion Libido Hormones Blood sugar Heart & lipids Skin & hair Immunity Longevity

Type:All Supplements Peptides Medications Substances Lifestyle Methods SARMs OtherResearch-backed only

33 results

149

PhenibutSubstance

Anxiety Mood Sleep

92% report better Mood

74 reports

MixedBResearch: Moderate

244

PsilocybinSubstance

Mood Anxiety Focus

93% report better Mood

59 reports

Mostly positiveAResearch: Strong

350

KratomSubstance

Mood Anxiety Energy

87% report better Mood

47 reports

MixedBResearch: Moderate

446

BromantaneSubstance

Energy Focus Mood

96% report better Mood

26 reports

Mostly positiveBResearch: Moderate

552

CaffeineSubstance

Energy Focus Anxiety

70% report better Mood

74 reports

MixedAResearch: Strong

654

LSDSubstance

Mood Focus Anxiety

84% report better Mood

19 reports

MixedAResearch: Strong

737

LSD MicrodoseSubstance

Mood Focus Anxiety

100% report better Mood

10 reports

Mostly positiveBResearch: Moderate

836

CannabisSubstance

Sleep Mood Anxiety

67% report better Mood

21 reports

MixedAResearch: Strong

946

NicotineSubstance

Focus Energy Mood

57% report better Mood

28 reports

MixedAResearch: Strong

1060

Yerba MateSubstance

Energy Focus Mood

100% report better Mood

5 reports

Mostly positiveAResearch: Strong

1126

PsychedelicsSubstance

Mood Energy

100% report better Mood

5 reports

MixedAResearch: Strong

1221

Psilocybin MicrodoseSubstance

Mood Energy Anxiety

100% report better Mood

5 reports

Mostly positiveBResearch: Moderate

1334

Nicotine GumSubstance

Focus Energy Anxiety

86% report better Mood

7 reports

MixedAResearch: Strong

1428

TesofensineSubstance

Mood Energy Weight loss

100% report better Mood

4 reports

Mostly positiveBResearch: Moderate

1527

DmtSubstance

Mood

100% report better Mood

4 reports

Mostly positiveAResearch: Strong

1614

DextromethorphanSubstance

Mood

100% report better Mood

4 reports

MixedAResearch: Strong

1743

Black TeaSubstance

Mood Energy Focus

100% report better Mood

3 reports

Mostly positiveAResearch: Strong

1831

Methylene BlueSubstance

Energy Focus Mood

100% report better Mood

3 reports

Mostly positiveAResearch: Strong

1923

MDMASubstance

Mood Anxiety Memory

47% report better Mood

15 reports

MixedAResearch: Strong

2042

AmphetaminesSubstance

Focus Energy Mood

75% report better Mood

4 reports

MixedAResearch: Strong

2143

Nicotine PatchSubstance

Focus Energy Memory

100% report better Mood

2 reports

Mostly positiveAResearch: Strong

2223

LSD MicrodosingSubstance

Focus Energy Mood

100% report better Mood

2 reports

MixedBResearch: Moderate

2323

MarijuanaSubstance

Sleep Focus Memory

100% report better Mood

2 reports

MixedAResearch: Strong

2421

Microdosing MushroomsSubstance

Mood Anxiety Energy

100% report better Mood

2 reports

Mostly positiveBResearch: Moderate

2520

MescalineSubstance

Mood

100% report better Mood

2 reports

Mostly positiveBResearch: Moderate

2614

Nicotine VapeSubstance

Focus Mood

100% report better Mood

2 reports

MixedBResearch: Moderate

2735

Nicotine PatchesSubstance

Focus Mood

67% report better Mood

3 reports

Mostly positiveAResearch: Strong

2825

THCSubstance

Anxiety Sleep Memory

40% report better Mood

5 reports

MixedAResearch: Strong

2925

WeedSubstance

Anxiety Sleep Mood

50% report better Mood

2 reports

MixedAResearch: Strong

3019

CocaineSubstance

Focus Energy Mood

50% report better Mood

2 reports

Mostly negativeAResearch: Strong

3115

DxmSubstance

Mood Focus

50% report better Mood

2 reports

Mostly negativeAResearch: Strong

3212

MethamphetamineSubstance

Focus Mood

50% report better Mood

2 reports

Mostly negativeAResearch: Strong

337

Cannabis EdiblesSubstance

Mood Anxiety

50% report better Mood

2 reports

MixedBResearch: Moderate

Minimum 2 reports per entry. Information only — not medical advice. How rankings work