People mainly take Nicotine Vape for focus, mood. Based on 6 first-hand reports and 1 meta-analyses & systematic reviews in the medical literature. Ranked #1250 of 1,974 overall.
Of reports that state an outcome, 17% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Thirdhand nicotine vape residue contributes to changes in some cells in mouse models but not others. Data available to date provide no convincing evidence of likely significant harm to humans. Further investigation is warranted to confirm or deny this impression.
PubMed 40283694 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“vaping, especially in an adolescent, does promote instant gratification - i want to feel different and then immediately i feel different”
“My sleep is literally so bad I think it's affecting my health. My skin is dry. My eyes don't look healthy. Anxious. The dentist said vaping has been making my mouth dry and gum health much worse.”
“I could easily see that with nicotine gum, with a vape however, it's not as easy but still possible for some. The amount of people I know who created an addiction out of no where with the juul is substantially large.”
“Vapes and cigs are different because the lungs are the one of the quickest routes of administering a drug, and this is a problem because fast-acting drugs are far more likely to be abused.”
“Had a juul for years and finally tossed that shit a few weeks ago. Never again.”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate