Find out what actually works — before you buy it.
PlainPill rates 1,974 supplements, nootropics and peptides using 49,653 real-world user reports and the clinical research behind each one. No affiliate links in the rankings.
1,974 substances · 49,653 user reports from 8,217 discussions · 779 with a research grade · how we rate
What do you want to improve?
Rankings by goal — sorted by how many people report it helped.
Top rated overall
User score: share of positive reports, weighted by volume and ratings.
Backed by research and users
High user scores and a solid base of meta-analyses and clinical trials.
Where the numbers come from
User reports. Thousands of first-hand accounts from health and supplement communities are read one by one, recording what people took, how much, and what happened.
Clinical research. Each substance is matched against PubMed — meta-analyses, randomized trials, and what those reviews concluded.
No hand edits. Every score is computed, every quote links to its source, and sponsors never touch the rankings. Full methodology