Best for anxiety

324 options people report for stress, calm and social anxiety, ranked by the share of users who say it improved — weighted by how many reports there are.

Weight loss Appetite Focus Energy Sleep Anxiety Mood Memory Performance Recovery Pain & inflammation Digestion Libido Hormones Blood sugar Heart & lipids Skin & hair Immunity Longevity

Type:All Supplements Peptides Medications Substances Lifestyle Methods SARMs OtherResearch-backed only

63 results

149

PropranololMedication

Anxiety Sleep Focus

97% report better Anxiety

35 reports

Mostly positiveAResearch: Strong

241

TianeptineMedication

Mood Anxiety Focus

93% report better Anxiety

15 reports

MixedAResearch: Strong

331

GabapentinMedication

Anxiety Sleep Mood

80% report better Anxiety

20 reports

MixedAResearch: Strong

450

XanaxMedication

Anxiety Sleep Focus

82% report better Anxiety

17 reports

MixedBResearch: Moderate

545

TestosteroneMedication

Performance Mood Libido

81% report better Anxiety

16 reports

Mostly positiveAResearch: Strong

646

MemantineMedication

Mood Focus Anxiety

91% report better Anxiety

11 reports

MixedAResearch: Strong

734

BaclofenMedication

Anxiety Mood Sleep

100% report better Anxiety

8 reports

Mostly positiveAResearch: Strong

857

GuanfacineMedication

Focus Anxiety Sleep

100% report better Anxiety

7 reports

Mostly positiveAResearch: Strong

921

BenzodiazepinesMedication

Anxiety Mood Memory

67% report better Anxiety

15 reports

MixedResearch pending

1036

LexaproMedication

Mood Anxiety Libido

78% report better Anxiety

9 reports

MixedBResearch: Moderate

1127

EtifoxineMedication

Anxiety

100% report better Anxiety

5 reports

Mostly positiveBResearch: Moderate

1225

LorazepamMedication

Anxiety

100% report better Anxiety

5 reports

MixedAResearch: Strong

1321

SSRIMedication

Mood Libido Anxiety

100% report better Anxiety

5 reports

Mostly negativeResearch pending

1422

BuspironeMedication

Anxiety Mood

75% report better Anxiety

8 reports

MixedAResearch: Strong

1531

ZoloftMedication

Mood Anxiety Energy

83% report better Anxiety

6 reports

Mostly positiveBResearch: Moderate

1628

FluoxetineMedication

Mood Anxiety Energy

83% report better Anxiety

6 reports

MixedAResearch: Strong

1724

SertralineMedication

Anxiety Mood

83% report better Anxiety

6 reports

MixedAResearch: Strong

1834

ClonazepamMedication

Anxiety Focus Energy

100% report better Anxiety

4 reports

MixedAResearch: Strong

1926

AtivanMedication

Anxiety Sleep

100% report better Anxiety

4 reports

Mostly positiveAResearch: Strong

2019

EffexorMedication

Anxiety Mood

100% report better Anxiety

4 reports

MixedBResearch: Moderate

2132

MethylphenidateMedication

Focus Mood Anxiety

58% report better Anxiety

12 reports

MixedAResearch: Strong

2221

PregabalinMedication

Anxiety Mood Memory

71% report better Anxiety

7 reports

MixedAResearch: Strong

2347

TRTMedication

Mood Energy Hormones

80% report better Anxiety

5 reports

Mostly positiveAResearch: Strong

2436

KetamineMedication

Mood Anxiety Heart & lipids

80% report better Anxiety

5 reports

MixedAResearch: Strong

2524

ProzacMedication

Mood Anxiety Libido

100% report better Anxiety

3 reports

MixedAResearch: Strong

2622

Intranasal InsulinMedication

Focus Memory Energy

100% report better Anxiety

3 reports

MixedAResearch: Strong

2719

ClonidineMedication

Anxiety Sleep Mood

100% report better Anxiety

3 reports

MixedAResearch: Strong

2814

AfobazoleMedication

Anxiety Memory Sleep

100% report better Anxiety

3 reports

MixedResearch pending

2914

BenzosMedication

Anxiety Sleep

100% report better Anxiety

3 reports

MixedResearch pending

3018

SsrisMedication

Mood Anxiety Libido

67% report better Anxiety

6 reports

Mostly negativeResearch pending

3119

Beta BlockersMedication

Anxiety Sleep

75% report better Anxiety

4 reports

Mostly positiveAResearch: Strong

3229

EscitalopramMedication

Mood Anxiety Energy

57% report better Anxiety

7 reports

MixedAResearch: Strong

3362

TadalafilMedication

Libido Performance Mood

100% report better Anxiety

2 reports

Mostly positiveAResearch: Strong

3441

ArmodafinilMedication

Focus Energy Mood

100% report better Anxiety

2 reports

Mostly positiveAResearch: Strong

3531

Low Dose NaltrexoneMedication

Focus Energy Mood

100% report better Anxiety

2 reports

Mostly positiveAResearch: Strong

3630

MirtazapineMedication

Sleep Mood Anxiety

100% report better Anxiety

2 reports

MixedAResearch: Strong

3725

HydroxyzineMedication

Sleep Anxiety

100% report better Anxiety

2 reports

MixedAResearch: Strong

3823

NSI-189 PhosphateMedication

Focus Anxiety Mood

100% report better Anxiety

2 reports

Mostly positiveResearch pending

3919

Ketamine TherapyMedication

Mood Anxiety

100% report better Anxiety

2 reports

Mostly positiveBResearch: Moderate

4015

KlonopinMedication

Anxiety Sleep Memory

100% report better Anxiety

2 reports

Mostly negativeDResearch: None

4114

AlprazolamMedication

Anxiety Focus Sleep

100% report better Anxiety

2 reports

MixedAResearch: Strong

4214

DiazepamMedication

Anxiety Sleep

100% report better Anxiety

2 reports

Mostly negativeAResearch: Strong

4314

FluvoxamineMedication

Anxiety Mood Focus

100% report better Anxiety

2 reports

MixedResearch pending

4414

ImidazenilMedication

Anxiety Focus Sleep

100% report better Anxiety

2 reports

Mostly positiveResearch pending

4514

Ketamine InfusionsMedication

Anxiety Mood

100% report better Anxiety

2 reports

MixedAResearch: Strong

4614

OlanzapineMedication

Anxiety Sleep Focus

100% report better Anxiety

2 reports

MixedResearch pending

477

OxazepamMedication

Anxiety Sleep

100% report better Anxiety

2 reports

MixedResearch pending

4843

SelegilineMedication

Mood Focus Energy

50% report better Anxiety

6 reports

MixedAResearch: Strong

4953

AdderallMedication

Focus Mood Energy

28% report better Anxiety

29 reports

MixedAResearch: Strong

5014

EtizolamMedication

Anxiety Focus Sleep

67% report better Anxiety

3 reports

Mostly negativeBResearch: Moderate

5154

WellbutrinMedication

Mood Energy Focus

50% report better Anxiety

4 reports

MixedBResearch: Moderate

5228

BenadrylMedication

Sleep Anxiety Focus

50% report better Anxiety

4 reports

MixedBResearch: Moderate

5336

VyvanseMedication

Focus Mood Energy

29% report better Anxiety

14 reports

MixedBResearch: Moderate

5446

ModafinilMedication

Focus Energy Mood

21% report better Anxiety

33 reports

MixedAResearch: Strong

5524

VortioxetineMedication

Mood Memory Energy

50% report better Anxiety

2 reports

MixedAResearch: Strong

566

ZopicloneMedication

Sleep Anxiety

50% report better Anxiety

2 reports

MixedResearch pending

5738

BupropionMedication

Mood Energy Focus

22% report better Anxiety

9 reports

MixedAResearch: Strong

5831

ConcertaMedication

Focus Energy Anxiety

33% report better Anxiety

3 reports

MixedBResearch: Moderate

5922

VenlafaxineMedication

Anxiety Focus

33% report better Anxiety

3 reports

Mostly negativeAResearch: Strong

6029

RitalinMedication

Focus Mood Anxiety

18% report better Anxiety

11 reports

MixedAResearch: Strong

6149

FinasterideMedication

Skin & hair Libido Mood

0% report better Anxiety

3 reports

MixedAResearch: Strong

6225

Adderall XrMedication

Focus Mood Energy

0% report better Anxiety

2 reports

MixedBResearch: Moderate

6325

StimulantsMedication

Focus Anxiety

0% report better Anxiety

2 reports

MixedResearch pending

Minimum 2 reports per entry. Information only — not medical advice. How rankings work