PlainPill

Etifoxine

People mainly take Etifoxine for anxiety. Based on 10 first-hand reports and 1 meta-analyses & systematic reviews in the medical literature. Ranked #472 of 1,974 overall.

27
User score
Mostly positive
40% positive0% mixed0% negative60% unclear

Of reports that state an outcome, 100% are positive.

Clinical research
BModerate research base
1
meta-analyses
12
RCTs
113
papers

What Etifoxine does, according to users

Of the people who reported each effect, the share who said it got better.

betterno changeworse

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

BModerate research base

At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.

Am J Ther · 2020 · Meta-analysis / systematic review
Therapeutic Interventions for Adjustment Disorder: A Systematic Review

Conclusion: Psychotherapy seems indicated for mildly symptomatic adjustment disorder. Given the fact that adjustment disorder with severe symptoms is associated with a high risk of suicidal ideation and suicide attempts, clinicians must consider the potential benefit of using psychotropic agents such as benzodiazepines, antidepressants, or etifoxine.

PubMed 32520732 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

2-3 capsulesas reported
dailyas reported

Reported side effects

How often each side effect came up across all reports.

No side effects reported so far.

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“Swap out the benzo for Etifoxine or Emoxypine”
Source discussion ↗
“Glad to see etifoxine getting some love!”
Source discussion ↗
“I would describe its effects as a very mild benzo. It kind of downs my stresses and frustrations without sedating me. Downside is that it is very pricy”
Source discussion ↗
“fascinated by Etifoxine (Stressem), Picamilon, Pantogam/Pantogam Activ, and Emoxypine”
Source discussion ↗
“the predominant medication for increasing ALLO levels (the anti-anxiety drug Etifoxine) shows little to no signs of tolerance.”
Source discussion ↗
Top discussions (5)

Other options for anxiety

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate