People mainly take Testosterone for performance, mood, libido. Based on 180 first-hand reports and 75 meta-analyses & systematic reviews in the medical literature. Ranked #179 of 1,974 overall.
Of reports that state an outcome, 76% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: The guidelines also provide recommendations regarding identification of patients, dosing, monitoring, and follow-up. This Practice Pearl will discuss evidence-based testosterone therapy for management of HSDD in postmenopausal women.
PubMed 37314872 ↗Conclusion: Although studies directly comparing the safety of SC vs IM administration of testosterone esters are desirable, clinicians should consider discussing the SC route with their patients because it is easier to self-administer and has the potential to improve patient adherence.
PubMed 34698352 ↗Conclusion: The current evidence is of low certainty but does not support an association between testosterone use and VTE in men.
PubMed 30396049 ↗Conclusion: Despite historical beliefs that TTh increases the risk of CV disease, thromboembolic events, BPH, and PCa, recent evidence suggests that TTh conveys less risk than previously perceived. While caution should continue to be exercised, evidence suggests that TTh is a reasonable treatment option in many hypogonadal men who were previously excluded from TTh based on risk factors and prior health histories. Twitchell DK, Pastuszak AW, Khera M. Controversies in Testosterone Therapy. Sex Med Rev 2021;9:149-159.
PubMed 33309270 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“Combined with an anti inflammitory along with metformin it has improved my physical and mental health.”
“using test and HGH with fat rich diet, in this specific moment of the healing process is not going to make the changes he is expecting to have”
“I can get TRT prescribed but I self administer instead as higher levels improve my symptoms.”
“And TRT, why not state that? No way this happens in 4 months with those peptides.”
“M/55/5'9" [230 → 205lbs] – 6 months of consistency”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate