People mainly take Vyvanse for focus, mood, energy. Based on 144 first-hand reports and 5 meta-analyses & systematic reviews in the medical literature. Ranked #283 of 1,974 overall.
Of reports that state an outcome, 42% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: The safety and tolerability profile of LDX in individuals with ADHD is similar to that of other stimulants.
PubMed 24788672 ↗Conclusion: This model predicts that LDX may have a large treatment effect size in European adults with ADHD.
PubMed 25725594 ↗Conclusion: There is an urgent need for adequately powered, placebo-controlled, behavioural and neuroimaging studies with LDX (recruiting patients and/or individuals with subclinical BED symptoms) to further investigate the mechanism of action of the drug in treating BED. An improved understanding of the behavioural and neurochemical mechanisms of action of LDX could lead to the development of improved drug therapies to treat BED.
PubMed 34461386 ↗Conclusion: Our purpose is to provide an overview of the potential pharmacotherapies or compounds tested in established rodent models of binge eating behavior. These findings will help provide guidance for determining pharmacological effectiveness for potential novel or repurposed pharmacotherapies.
PubMed 37238615 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“I tried Vyvanse, modafinil, ritalin, adderall for concetration and attention... in terms of ROI they don't deliver and I'm better of without them”
“ADHD Medication (specifically Adderall/Vyvanse) impact on health and longevity”
“amphetamines like Adderall and Vyvanse makes all the difference in my motivation and general functioning”
“I take my Vyvanse as medicine. I don't take it to 'get shit done.'”
“Vyvanse helped immensely with my ADHD but the negative side effects were more than the benefits were worth.”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate