Conclusion: Current evidence suggests that there were significantly greater odds of PPHN with SSRI use during pregnancy. However, the clinical significance of this association remains modest and likely outweighed by the potential benefits of treatment of perinatal depression. The risk of PPHN associated with SSRI therapy might not warrant the recommendation to withdraw antidepressant therapy, as evidence from other studies show that untreated perinatal depression presents additional adverse maternal and fetal outcomes. Given the increasing prevalence of maternal depression and consequent use of antidepres
PubMed 30407100 ↗Lexapro
People mainly take Lexapro for mood, anxiety, libido. Based on 25 first-hand reports and 1 meta-analyses & systematic reviews in the medical literature. Ranked #278 of 1,974 overall.
Of reports that state an outcome, 56% are positive.
What Lexapro does, according to users
Of the people who reported each effect, the share who said it got better.
6 more with fewer than 3 reports
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“Lexapro didn't really help me at all, made me more lethargic and gave me way more brain fog if anything”
“Topiramate, Stablon, Lexapro, Quetiapin, Clonazepam”
“I'm on lexapro”
“After over a year of trying several different non-SSRI anxiety and depression medications, getting on escitalopram (lexapro) has had undeniable positive effects on me”
“I haven't always felt like this so I wanted to explore more options before starting that. He then tested for Lyme and testosterone. He wanted to start Lexapro. I haven't always felt like this so I wanted to explore more ”
Other options for mood
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate