PlainPill

What people actually say

4,935 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
“I’ve tried physical therapy, swimming, exercises, omega-3, turmeric, and other anti-inflammatory stuff—nothing seems to help.”
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“Whenever I add raw Turmeric & Ginger to my stack, I feel any existing brain fog disappear within 15 minutes... That's very unlikely that chewing on turmeric would affect you so strongly and so quickly.”
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“Turmeric and Magnesium make me feel like absolute shit if I take them before sunset.”
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SemaglutideMostly positive
“I've lost 35lbs since then and now I'm in the Healthy range on BMI. My IBSD has virtually disappeared.”
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SemaglutideMostly positive
“I tried ozempic at first. Made me really sick so I stopped.”
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SemaglutideMostly positive
“I recently cycled off Ozempic after 6 months. It did not agree with me...profund depression...profound depression(something I dont normally have an issue with).”
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SemaglutideMostly positive
“I’ve noticed since getting on the wegovy I have felt like I’ve been in a strange depression. I’m not explicitly suicidal but I feel nothing - no happiness, no love, no hope.”
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TianeptineMostly positive
“It has really improved the quality of my life, more than anything else I have taken.”
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TianeptineMostly positive
“it made my head foggy and made me more anxious. Noticed no improvement in mood.”
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TianeptineMostly positive
“I take 15mg 3x daily, and it keeps me out of depression and in a good mood. It also helps me focus in class more.”
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TianeptineMostly positive
“I was able to successfully quit using low doses of tianeptine. But be careful as that can be an even worse addiction.”
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ZMAMostly positive
“The only thing that is affordable and has seemed to help me is ZMA. I only have the anecdote that ZMA seemed to improve sex drive, sleep, dreams, erectile quality when I first t began taking it at age 18.”
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ZMAMostly positive
“So then I started taking ZMA since I read it does wonders for energy and helps ensure proper sleep. I proceeded to feel worse, anhedonic and basically depressed.”
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ZMAMostly positive
“supplementing ZMA, D3, creatine, sardines/DHA&EPA/other fatty fish works well for my health, sleep, and muscle gain.”
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ZMAMostly positive
“my sleep quality has improved tremendously. It's hard to put into words but I feel like I'm sleeping on clouds. I'm also sleeping fewer hours but feeling more rested in the morning.”
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CistancheMostly positive
“Cistanche extract increases my drive, energy and vigor. It makes me want to attack life. I get better sleep...My work ethic has improved. My memory. my attitude towards life. Every facet of my life has been altered in a positive meaningful way.”
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CistancheMostly positive
“Fucking hated it. After just a week on it my libido went non existent. It left me feeling numb, unmotivated and lazy.”
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CistancheMostly positive
“Increases energy, boosts my mood, makes me feel more chilled, better libido, I feel more confident.”
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CistancheMostly positive
“cistanche is the only thing I had to stop taking because it worked too well...cistanche is the only thing that made me horny all the time.”
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ALAMostly positive
“I also take alcar, alpha lipoic acid, choline, and pqq, but... there is some difference with these, but not as major as with CoQ10.”
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ALAMostly positive
“ALCAR+alpha lipoic acid works as well as Adderall. Actually, it's a bit better for me—it wears off more slowly and doesn't interfere with sleep the way Adderall does.”
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ALAMostly positive
“ALA fixed the issue almost instantly, so I usually don't take ALCAR without the ALA.”
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ALAMostly positive
“R-ALA - has shrunk keloids that I was told would never go away and helped with general over all MS body pain”
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PsilocybinMostly positive
“Mushrooms make me a better husband and a better human all around. Sometimes I don’t feel the urge to have sex while I’m on a dose, but I feel much more connected afterward. Low dose is definitely an aphrodisiac in my experience.”
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PsilocybinMostly positive
“doing shrooms helped a lot. I felt really peaceful...This slowly went away, and was gone the next day.”
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PsilocybinMostly positive
“I also micro dose psilocybin on and off and macro dose once in awhile. This definitely helps with my overall well-being and mood.”
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PsilocybinMostly positive
“The psilocybin just made my mind quieter and allowed me to focus on one thing at a time. Its also helped me just stay in a positive mood which helped my anxiety.”
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“St. John's Wort, Passion Flower, Hops, and Skullcap. My sleep improved with those.”
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“even the nootropics that some communities swear by did nothing for me (some that come to mind - racetams, tyrosine/NALT, NAC, methylated B vitamins...”
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“I dabbled with 5-HTP ... and St. John's Wort ... and found them to have some nice anti-anxiety / sedating effects.”
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“I am taking Saint John's Wort and Bacopa now to modulate my serotonin system, as well as trimethylglycine to help boost catecholamine production. That is helping a lot.”
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Lithium OrotateMostly positive
“The lithium is absolutely curbing my mania... My social anxiety is 100% gone when I take lithium orotate.”
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Lithium OrotateMostly positive
“Been taking 10-20 mg for a week or so... my mood is more stable. Rumination is not really there... Highly recommend... Ended up getting sexual dysfunction from it, stopped it.”
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Lithium OrotateMostly positive
“I take 5mg LiOr every morning upon waking for ADHD, and I've experienced nothing but massive benefits...Many people complain about lethargy and brain fog at these doses.”
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Lithium OrotateMostly positive
“Mood has increased, depression is decreased and anxiety no longer exists in my life. It has been a miracle drug for me.”
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DHEAMixed
“DHEA, minimum 50 mg was a huge game changer for my wife. More energy, libido, dopamine/happy mood, concentration- everything.”
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DHEAMixed
“I started off with like 25mg and have upped it over time to like 150mg now... I’m usually more assertive as well, similar to Tribulus but it actually helps me sleep.”
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DHEAMixed
“Once I started taking dhea...I felt significantly better. It raises T, has positive effects on both gaba and dopamine.”
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DHEAMixed
“DHEA might help also. I sleep very deep and have vivid dreams on it. I take 25mg an hour before bed.”
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Whey ProteinMostly positive
“Coffee with cream, has to be a cream or fake creamer with a whey protein, doesn't. It gives me a gentle but potent energy boost with no headache and no jitters.”
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