Lithium Orotate
People mainly take Lithium Orotate for mood, anxiety, sleep. Based on 220 first-hand reports and 0 meta-analyses & systematic reviews in the medical literature. Ranked #58 of 2,750 overall.
Of reports that state an outcome, 75% are positive.
What Lithium Orotate does, according to users
Of the people who reported each effect, the share who said it got better.
3 more with fewer than 3 reports
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
No randomized controlled trials in humans found on PubMed. The grade measures how much human research exists — read the conclusions below for what it found.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“Why not lithium instead? ... Bioavailability of lithium orotate is high, effective dose is very small. Proven to also modualte mood”
“Last week I started lithium orotate to decrease anxiety and mood swings, although it works amazingly”
“1-2 tablets of lithium orotate from Advanced Research - Hans Niepers brand.”
“Try lithium orotate sublingually to help you sleep... I found that 5mg is too strong so I've been experimenting with 1mg and find it very relaxing.”
“I've found sublingual lithium to be great for falling asleep when I'm having trouble.”
Lithium Orotate compared
Other options for mood
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 3, 2026. How we rate