People mainly take DHEA for libido, mood, energy. Based on 102 first-hand reports and 215 meta-analyses & systematic reviews in the medical literature. Ranked #261 of 1,974 overall.
Of reports that state an outcome, 77% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Vaginal estrogen, vaginal DHEA, oral ospemifene, and vaginal moisturizers may improve some GSM symptoms in the short term. Few long-term data exist on efficacy, comparative effectiveness, tolerability, and safety of GSM treatments.
PubMed 39250810 ↗Conclusion: For patients with POR, controlled ovarian stimulation protocols using adjuvant treatment with DHEA, CoQ10 and GH showed better clinical outcomes in terms of achieving pregnancy, and a lower dosage of gonadotrophin required for ovulation induction. Furthermore, high-level RCT studies using uniform standards for POR need to be incorporated into future meta-analyses.
PubMed 32045470 ↗Conclusion: Compared with COS regimen, the adjuvant use of CoQ10, DHEA and GH before IVF may have a better clinical effect on the pregnancy outcome of POR patients. TEAS needs careful consideration in improving the clinical pregnancy rate. Future large-scale RCTs with direct comparisons are needed to validate or update this conclusion.
PubMed 37464357 ↗Conclusion: The KD seems to offer a substantial benefit in improving all the anthropometric, metabolic, and hormonal parameters evaluated. Broader studies involving women with PCOS may provide further insight into the effects of a low glycemic index diet in this group of patients.
PubMed 39978319 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“DHEA might help also. I sleep very deep and have vivid dreams on it. I take 25mg an hour before bed.”
“You might be better with DHEA as only converts to testosterone in small amounts”
“my testosterone was getting quite high (for a woman) when I was taking it twice a day compared to when I was off it completely”
“Also DHEA”
“DHEA takes a little time to work, but does function well as a test booster. I have consistently been much more easily aroused while a few weeks deep into a DHEA cycle.”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate