Conclusion: Analysis revealed that chronic and without professional guidance use of whey protein supplementation may cause some adverse effects specially on kidney and liver function. Presented data support a need for future studies co-relating the use of different types of whey protein with and without exercise to better see the impact on human physical health.
PubMed 32702243 ↗Whey Protein
People mainly take Whey Protein for performance, recovery, digestion. Based on 60 first-hand reports and 97 meta-analyses & systematic reviews in the medical literature. Ranked #271 of 1,974 overall.
Of reports that state an outcome, 81% are positive.
What Whey Protein does, according to users
Of the people who reported each effect, the share who said it got better.
2 more with fewer than 3 reports
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: This review confirms that WP can improve various aspects of older adult with sarcopenia, thereby enhancing their overall physical condition. More studies should be conducted to validate this result and further explore the effects of WP and RT in patients with sarcopenia.
PubMed 38350303 ↗Conclusion: WP supplementation during RET is more effective in increasing handgrip strength and skeletal muscle mass in older people with Sarcopenia compared with RET with or without placebo supplementation. However, the effect sizes were small, and the MD did not exceed the minimally important clinical difference. The quality of the evidence was low to very low according, to the GRADE approach. Further research is needed in this field.
PubMed 37571361 ↗Conclusion: WP supplementation did not show a significantly different effect on fat mass or body weight loss in both the subgroups; (4) Conclusions: In postmenopausal women, WP supplementation only in combination with RT enhances BC and LLLM compared to placebo controls. Without RT, WP has no significant benefit on muscle strength or lean mass.
PubMed 36235862 ↗Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“currently taking: glucosamine, whey protein, l-arginine, multivitamin, omega 3, magnesium, collagen (7g)”
“I take a smoothie with whey protein and some fruits but need to add something else to help gain weight.”
“*Whey Protein* - RSP Truefit (Question: Is isolate better?”
“Whey protein.”
“protein-forward first meal at noon, whey shake at 6pm”
Top discussions (5)
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Other options for performance
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate