PlainPill

What people actually say

614 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
AndrographisMostly positive
“Have you tried Andrographis? For me it has been a very interesting one since it's helped me be a little more chill and my sleep has been amazing”
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AndrographisMostly positive
“try andrographis. That herb is a miracle, I swear by it. Especially for respiratory issues”
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ClaMostly negative
“CLA (with pomegranite seed oil) and fish oil for a while. I have auto-immune issues and they really help with inflammation and itchy dry skin. It keeps the anxiety down too.”
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ClaMostly negative
“I used CLA for about 3 months beginning last November, but never noticed any results from it, heard the same from other users”
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ClaMostly negative
“I've actually had great results dropping BF 1-2% taking CLA with no changes in diet or exercise”
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ClaMostly negative
“I took CLA for several months and it had precisely 0 effect”
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“One I'm on now is called Tesofensine. About 70 days in. I got off anti-depressants and this one peptide has me feeling like a god, better workouts, less anxiety, higher confidence, sex drive thru the roof.”
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“I'm now five months in with the other therapies and extremely happy. I feel like a 20 year old. Mood, focus, energy”
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“Tesofensine stood out for dopamine, energy, and executive drive. I’d suggest morning dosing so it doesn’t interfere with sleep.”
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“I've been taking it for 3 days, 125ug the first two days and 250ug today... completely removed my symptoms of ADHD-PI and chronic dysthymia.”
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“I will wake up and take Yohimbine HCL 14g + Synephrine 50g + Coffee”
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“I use about 100mg of Synephrine in the morning and that helps a little bit.”
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“Synephrine, but in my experience I would probably need a huge dose to get 1/2 the effects of ephedrine.”
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“I'm a fan of small doses of synephrine (no more than 50-100mg/day)”
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Chia SeedsMostly positive
“My stool came so moist and soft, easily passing through... I can't remember my stomach and colon feeling so good”
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Chia SeedsMostly positive
“I'm into 20g of chia seeds (soaked overnight) but the dirty hole is back”
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Chia SeedsMostly positive
“This and chia seeds has helped me a lot regarding digestion issues but it helps ALOT with my blood sugar”
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Chia SeedsMostly positive
“I added psyllium and chia seeds to my morning smoothie and kept the rest of my diet the same. My ldl went down 21 points into the normal range.”
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“I am taking Saint John's Wort and Bacopa now to modulate my serotonin system, as well as trimethylglycine to help boost catecholamine production. That is helping a lot.”
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“It helped me tons initially, just in the last couple of days increased my Acetylcholine for some reason.”
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“I have found that it has completely "cured" my hypoglycemia.”
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“the tmg fucked with my cholesterol and I was worse off”
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Weight TrainingMostly positive
“I’d spend the money on a gym membership instead as that will have the best positive impact on energy.”
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Weight TrainingMostly positive
“what is a good way to raise Testosterone. I just started doing weights 3x a week, I guess weights is the answer?”
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Weight TrainingMostly positive
“I wonder if this could be mostly mitigated with some regular weight training? Its the best way to prevent bone loss in the elderly.”
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CagrilintideMostly positive
“Cagri was a game changer for me. I added 1mg and thats been more than enough.”
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CagrilintideMostly positive
“Every needs to be aware of the severe fatigue that shows up for some ppl, for me it almost landed me in a depressive episode.”
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CagrilintideMostly positive
“Also using Cagri / Tirz to cut while weight training 4 x per week and logging calories / macros. Working great for me, I’m maintaining weight but my body composition is changing for the better.”
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CagrilintideMostly positive
“added in Cagrilinitide for the last 2 weeks because I felt my hunger rise, and it definitely helped a ton”
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Paleo DietMostly positive
“now on non-super-strict paleo but without alco-sugary-stimulant stuff i feel really good!”
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Paleo DietMostly positive
“since switching to the Paleo Diet it seems worse than before. Everything else about my health is great but I'm so cold”
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Paleo DietMostly positive
“Have you tried a Paleo diet? Here's what works for me. I hope that it will change your life.”
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Paleo DietMostly positive
“Cutting the sugars & grains made me feel better fast”
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BetaineMostly positive
“trimethylglycine/betaine, sam-e, and glycine... These all have helped with my own depression, anxiety, and anhedonia.”
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BetaineMostly positive
“I took Betaine, my chronic bloating triggered the vagus heavily too, the Betaine removed bloating.”
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BetaineMostly positive
“Creatine, hmb and betaine has been working pretty good for me.”
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BetaineMostly positive
“The one I find most exciting is betaine aka trimethylglycine.”
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“the improvements in sleep quality made a dramatic improvement in my overall quality of life and the impact was noticeable within a week.”
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“I did a cycle for 4 months and didn’t see much for results... developed some carpel tunnel side effects, water retention”
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“IPA and CJC have been life changing for my injuries with non of the shitty side effects”
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User reports — what people say about supplements — PlainPill