People mainly take Melanotan Ii for skin & hair, libido, weight loss. Based on 18 first-hand reports and 1 meta-analyses & systematic reviews in the medical literature. Ranked #355 of 1,974 overall.
Of reports that state an outcome, 87% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Almost all studies are in the preclinical phase. There are currently no effective clinical treatments for MC4R-deficient obese patients, although MC4R agonists are being developed and are entering phase I and II trials.
PubMed 23774329 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“weirdly missing peptides like pt-141, mt-2, kisspeptin-10, etc.”
“MT2 for color”
“Reta, MT2, KLOW right now. Also on Test C for TRT.”
“Mt-2 (just started)”
“Most people use it for getting tan and it works dramatically”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate