PlainPill

Collagen

People mainly take Collagen for skin & hair, recovery, pain & inflammation. Based on 150 first-hand reports and 9 meta-analyses & systematic reviews in the medical literature. Ranked #86 of 1,974 overall.

51
User score
Mixed
24% positive16% mixed6% negative54% unclear

Of reports that state an outcome, 52% are positive.

Clinical research
AStrong research base
9
meta-analyses
22
RCTs
89
papers

What Collagen does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

J Cosmet Dermatol · 2020 · Meta-analysis / systematic review
Collagen supplementation for skin health: A mechanistic systematic review

Conclusion: In this systematic review, three different mechanisms of action were clarified for the intervention. Direct effects of collagen peptides on fibroblasts, M2-like macrophages, and oral tolerance-related mechanisms are the possible mechanisms for the beneficial effects of collagen supplementation.

PubMed 32436266 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

7 gdaily
20-40 gdaily
before bedas reported
10 g5x/week
6,000 mgdaily
dailyas reported

Reported side effects

How often each side effect came up across all reports.

fatigue ×2histamine episode ×1joint inflammation ×1kidney strain ×1insomnia ×1drowsiness ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

Other options for skin & hair

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate