PlainPill

Maca vs Melanotan Ii for libido

Short answer: For libido, more users report improvement with Melanotan Ii — 96% of 47 reports, versus 88% of 112 for Maca.

Maca has 13 meta-analyses and 13 randomized trials on PubMed; Melanotan Ii has 1 and 1.

Based on 299 reports about Maca and 145 about Melanotan Ii. Not medical advice.

Maca
Supplement
Melanotan Ii
Peptide
User score5161
Verdict
Mixed
Mostly positive
Positive
of reports that state an outcome
52%63%
Reports299145
ResearchAResearch: StrongBResearch: Moderate
Meta-analyses / RCTs13 / 131 / 1
Mainly used for
Weight loss
% reporting improvement
—100% (11)
Appetite
% reporting improvement
—67% (6)
Focus
% reporting improvement
90% (10)—
Energy
% reporting improvement
82% (40)—
Sleep
% reporting improvement
40% (5)0% (4)
Anxiety
% reporting improvement
43% (7)—
Mood
% reporting improvement
87% (30)40% (5)
Performance
% reporting improvement
100% (4)100% (5)
Digestion
% reporting improvement
0% (2)—
Libido
% reporting improvement
88% (112)96% (47)
Hormones
% reporting improvement
73% (15)—
Heart & lipids
% reporting improvement
—33% (3)
Skin & hair
% reporting improvement
—91% (67)
Immunity
% reporting improvement
100% (2)100% (2)
Common side effectsanxiety, stomach issues, insomnia, acnenausea, flushing, freckles, darkened moles
Typical dose reporteddailyNot listed
Maca
Latest review conclusion

Conclusion: The evidence from the included studies suggests unclear effects of maca on semen quality parameters in both men experiencing infertility and healthy men. However, the total number of RCTs and the total sample size were too small to draw firm conclusions.

Front Pharmacol, 2022 ↗
What a user said
“The better experiences were with gelatinized maca powder, 20g or so in a cup and my cock was hard as El Peñón de Gibraltar.”
Full Maca profile →
Melanotan Ii
Latest review conclusion

Almost all studies are in the preclinical phase. There are currently no effective clinical treatments for MC4R-deficient obese patients, although MC4R agonists are being developed and are entering phase I and II trials.

Int J Obes (Lond), 2014 ↗
What a user said
“I've found that getting sun within 3-12 hours will produce the desired result.”
Full Melanotan Ii profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate