PlainPill

GHK-Cu vs Melanotan Ii for skin & hair

Short answer: For skin & hair, users rate them about the same: 87% report improvement with GHK-Cu (202 reports) and 88% with Melanotan Ii (84 reports).

GHK-Cu has 0 meta-analyses and 1 randomized trials on PubMed; Melanotan Ii has 1 and 1.

Based on 496 reports about GHK-Cu and 186 about Melanotan Ii. Not medical advice.

GHK-Cu
Peptide
Melanotan Ii
Peptide
Users say it helped62%helped223 reports · high confidence60%helped115 reports · high confidence
Verdict
Mostly positive
Mixed
ResearchCResearch: LimitedBResearch: Moderate
Meta-analyses / RCTs0 / 11 / 1
Mainly used for
Skin & hair
% reporting improvement
87% (202)88% (84)
Libido
% reporting improvement
—96% (48)
Pain & inflammation
% reporting improvement
90% (31)—
Recovery
% reporting improvement
96% (27)—
Weight loss
% reporting improvement
88% (8)100% (12)
Common side effectsinjection site, redness, stinging, injection painnausea, flushing, freckles, moles
Typical dose reportedNot listedNot listed
GHK-Cu
What a user said
“Love it. 44 F. Totally helped even out my skin tone (Irish red cheeks), reduced wrinkles on my forehead and neck, thickened my hair which had been thinning, and grew my eye lashes.”
Full GHK-Cu profile →
Melanotan Ii
Latest review conclusion

Almost all studies are in the preclinical phase. There are currently no effective clinical treatments for MC4R-deficient obese patients, although MC4R agonists are being developed and are entering phase I and II trials.

Int J Obes (Lond), 2014 ↗
What a user said
“I've found that getting sun within 3-12 hours will produce the desired result.”
Full Melanotan Ii profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate