PlainPill

HGH

People mainly take HGH for performance, recovery, weight loss. Based on 118 first-hand reports and 14 meta-analyses & systematic reviews in the medical literature. Ranked #245 of 1,974 overall.

38
User score
Mostly positive
32% positive11% mixed5% negative52% unclear

Of reports that state an outcome, 67% are positive.

Clinical research
AStrong research base
14
meta-analyses
146
RCTs
4,709
papers
High-risk compound. Peptides are not approved as supplements, carry serious and sometimes irreversible risks, are banned in competitive sport and may be restricted where you live. Nothing here is a recommendation to use it.

What HGH does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

Sports Med · 2022 · Meta-analysis / systematic review
Effects of Exercise Training on Anabolic and Catabolic Hormones with Advanced Age: A Systematic Review

Conclusion: In conclusion, findings from this systematic review suggest that exercise training increases basal levels of testosterone, IGF-1, SHBG, hGH and DHEA in both male and females over 40 years of age. The increases in blood levels of these hormones were independent of the mode, duration and intensity of the training programs. However, the effects of long-term exercise training on cortisol and insulin levels in elderly people are less clear.

PubMed 34936049 ↗
Cochrane Database Syst Rev · 2001 · Meta-analysis / systematic review
Growth hormone for children with chronic renal failure

Conclusion: On average, one year of 28 IU/m(2)/wk hGH in children with CRF results in a 4 cm/yr increase in height velocity above that of untreated controls, however, it is not certain if this will result in an increase in final adult height. Benefits of longer courses or higher doses of treatment warrants further study.

PubMed 11687179 ↗
Cochrane Database Syst Rev · 2007 · Meta-analysis / systematic review
Recombinant growth hormone for children and adolescents with Turner syndrome

Conclusion: Recombinant human growth hormone (hGH) doses between 0.3 to 0.375 mg/kg/wk increase short-term growth in girls with Turner syndrome by approximately three (two) cm in the first (second) year of treatment. Treatment in one trial increased final height by approximately six cm over an untreated control group. Despite this increase, the final height of treated women was still outside the normal range. Additional trials of the effects of hGH carried out with control groups until final height is achieved would allow better informed decisions about whether the benefits of hGH treatment outweigh the r

PubMed 17253498 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

daily injectionsas reported
2-3 IUdaily
low dosesas reported
2 iudaily
4 iudaily
modest dosebefore bed

Reported side effects

How often each side effect came up across all reports.

water retention ×3fainting ×1fatigue ×1brain fog ×1bone growth ×1facial aging ×1insulin resistance ×1joint pain ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“HGH has been the biggest gift to my life.”
Source discussion ↗
“Maybe I'll bite the bullet and go the HGH route this fall with genotropin.”
Source discussion ↗
“HGH.”
Source discussion ↗
“The best I've found aren't peptides save one. Test, HGH, and Reta.”
Source discussion ↗
“HGH 4iu per day”
Source discussion ↗
Top discussions (5)

Other options for performance

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate