PlainPill

DHEA vs Vitamin D for hormones

Short answer: For hormones, users rate them about the same: 91% report improvement with DHEA (44 reports) and 91% with Vitamin D (75 reports).

DHEA has 215 meta-analyses and 637 randomized trials on PubMed; Vitamin D has 3,251 and 4,560.

Based on 306 reports about DHEA and 3,058 about Vitamin D. Not medical advice.

DHEA
Supplement
Vitamin D
Supplement
Users say it helped56%helped98 reports · medium confidence67%helped1,101 reports · high confidence
Verdict
Mixed
Mostly positive
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs215 / 6373,251 / 4,560
Mainly used for
Mood
% reporting improvement
87% (30)88% (393)
Energy
% reporting improvement
92% (26)87% (255)
Sleep
% reporting improvement
100% (5)52% (119)
Hormones
% reporting improvement
91% (44)91% (75)
Anxiety
% reporting improvement
86% (7)64% (90)
Common side effectsacne, vivid dreams, rage, virilizationinsomnia, anxiety, hypercalcemia, nausea
Typical dose reported25 mg / 1 hour before bed10,000-20,000 IU / daily
DHEA
Latest review conclusion

Vaginal estrogen, vaginal DHEA, oral ospemifene, and vaginal moisturizers may improve some GSM symptoms in the short term. Few long-term data exist on efficacy, comparative effectiveness, tolerability, and safety of GSM treatments.

Ann Intern Med, 2024 ↗
What a user said
“DHEA, minimum 50 mg was a huge game changer for my wife. More energy, libido, dopamine/happy mood, concentration- everything.”
Full DHEA profile →
Vitamin D
Latest review conclusion

These results indicate that the prevalence of vitamin D deficiency was more elevated in obese subjects. The vitamin D deficiency was associated with obesity irrespective of age, latitude, cut-offs to define vitamin D deficiency and the Human Development Index of the study location.

Obes Rev, 2015 ↗
What a user said
“First thing I noticed was my mood & libido, I have more 'feeling/sensitivity' down there.”
Full Vitamin D profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate