DHEA vs Testosterone for hormones
Short answer: For hormones, users rate them about the same: 91% report improvement with DHEA (44 reports) and 91% with Testosterone (101 reports).
DHEA has 215 meta-analyses and 637 randomized trials on PubMed; Testosterone has 75 and 125.
Based on 306 reports about DHEA and 924 about Testosterone. Not medical advice.
| DHEA Supplement | Testosterone Medication | |
|---|---|---|
| Users say it helped | 56%helped98 reports · medium confidence | 76%helped425 reports · high confidence |
| Verdict | Mixed | Mostly positive |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 215 / 637 | 75 / 125 |
| Mainly used for | ||
| Performance % reporting improvement | 75% (4) | 98% (180) |
| Mood % reporting improvement | 87% (30) | 89% (117) |
| Hormones % reporting improvement | 91% (44) | 91% (101) |
| Energy % reporting improvement | 92% (26) | 93% (88) |
| Libido % reporting improvement | 91% (32) | 90% (78) |
| Common side effects | acne, vivid dreams, rage, virilization | suppression, hair loss, acne, water retention |
| Typical dose reported | 25 mg / 1 hour before bed | Not listed |
Vaginal estrogen, vaginal DHEA, oral ospemifene, and vaginal moisturizers may improve some GSM symptoms in the short term. Few long-term data exist on efficacy, comparative effectiveness, tolerability, and safety of GSM treatments.
Ann Intern Med, 2024 ↗“DHEA, minimum 50 mg was a huge game changer for my wife. More energy, libido, dopamine/happy mood, concentration- everything.”
The guidelines also provide recommendations regarding identification of patients, dosing, monitoring, and follow-up. This Practice Pearl will discuss evidence-based testosterone therapy for management of HSDD in postmenopausal women.
Menopause, 2023 ↗“Feel the best I've ever felt in my life. TRT and peptides have been game changers for me!”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate