PlainPill

Vitamin D

People mainly take Vitamin D for mood, energy, sleep. Based on 1,505 first-hand reports and 3,251 meta-analyses & systematic reviews in the medical literature. Ranked #80 of 1,974 overall.

52
User score
Mostly positive
31% positive12% mixed4% negative53% unclear

Of reports that state an outcome, 66% are positive.

Clinical research
AStrong research base
3,251
meta-analyses
4,560
RCTs
93,302
papers

What Vitamin D does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

Nutrients · 2023 · Meta-analysis / systematic review
Psoriasis and Vitamin D: A Systematic Review and Meta-Analysis

Conclusion: No significant differences were found in PASI after 3, 6, and 12 months of supplementation. It is shown that 25(OH)D serum levels are significantly lower in psoriasis, but, although the granularity of RCT methodology may have influenced the pooled analysis, vitamin D supplementation did not seem to improve clinical manifestations.

PubMed 37571324 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

dailyas reported
10,000-20,000 IUdaily
5000 iualmost daily
dailydaily
30,000 IUdaily
above 50 ng/mLdaily

Reported side effects

How often each side effect came up across all reports.

insomnia ×28anxiety ×18fatigue ×16hypercalcemia ×10nausea ×6irritability ×5heart palpitations ×5depression ×4

What users say

Verbatim quotes, shortened only — each links to the original discussion.

Other options for mood

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate