PlainPill

Zinc

People mainly take Zinc for libido, mood, sleep. Based on 812 first-hand reports and 220 meta-analyses & systematic reviews in the medical literature. Ranked #200 of 1,974 overall.

43
User score
Mostly positive
23% positive9% mixed6% negative62% unclear

Of reports that state an outcome, 61% are positive.

Clinical research
AStrong research base
220
meta-analyses
555
RCTs
3,329
papers

What Zinc does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

J Glob Health · 2024 · Meta-analysis / systematic review
Zinc supplementation for acute and persistent watery diarrhoea in children: A systematic review and meta-analysis

Conclusion: Zinc should continue to be recommended in children under the age of 10 years with acute or persistent diarrhoea, but moderate certainty of evidence concludes that the dose of zinc should be reduced. However, further multi-country randomised clinical trials are required with a direct comparison to assess the appropriate dosage, duration and adverse effects.

PubMed 39641338 ↗
Nutrients · 2024 · Meta-analysis / systematic review
Efficacy of Zinc Supplementation in the Management of Primary Dysmenorrhea: A Systematic Review and Meta-Analysis

Conclusion: Zinc supplementation is an effective and well-tolerated option for reducing pain severity in women with primary dysmenorrhea. Doses as low as 7 mg/day of elemental zinc are sufficient to achieve significant pain relief, with longer durations (≥8 weeks) enhancing efficacy. The favorable safety profile and ease of use support the consideration of zinc supplementation as a practical approach to managing primary dysmenorrhea.

PubMed 39683510 ↗
J Trace Elem Med Biol · 2023 · Meta-analysis / systematic review
Correlation between serum zinc and testosterone: A systematic review

Conclusion: Furthermore, the effect degree of zinc on serum testosterone may vary depending on basal zinc and testosterone levels, zinc dosage form, elementary zinc dose, and duration. In conclusion, serum zinc was positively correlated with total testosterone, and moderate supplementation plays an important role in improving androgen.

PubMed 36577241 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

dailyas reported
75 mgas reported
every other dayas reported
before bedas reported
50-100 mgas reported
45 mgas reported

Reported side effects

How often each side effect came up across all reports.

nausea ×14fatigue ×10stomach issues ×10copper deficiency ×7copper depletion ×5brain fog ×5loss of ×5vertigo ×2

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“I also take D3, garlic and zinc that have proven effect in boosting immune system”
Source discussion ↗
“Can we take zinc and seleniumn together or not? I heard once that they are antagonists”
Source discussion ↗
“Zinc sends your libido through the roof if you're deficient.”
Source discussion ↗
“Zinc 50-100mg”
Source discussion ↗
“Have been supplementing with 45mg zinc and multivitamins as well.”
Source discussion ↗
Top discussions (5)

Other options for libido

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate