DHA vs DHEA for mood
Short answer: For mood, more users report improvement with DHA — 100% of 11 reports, versus 87% of 30 for DHEA.
DHA has 365 meta-analyses and 1,607 randomized trials on PubMed; DHEA has 215 and 637.
Based on 133 reports about DHA and 306 about DHEA. Not medical advice.
| DHA Supplement | DHEA Supplement | |
|---|---|---|
| Users say it helped | 76%helped39 reports · medium confidence | 56%helped98 reports · medium confidence |
| Verdict | Mostly positive | Mixed |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 365 / 1,607 | 215 / 637 |
| Mainly used for | ||
| Hormones % reporting improvement | — | 91% (44) |
| Mood % reporting improvement | 100% (11) | 87% (30) |
| Libido % reporting improvement | 100% (2) | 91% (32) |
| Energy % reporting improvement | 100% (3) | 92% (26) |
| Memory % reporting improvement | 80% (20) | — |
| Common side effects | None reported | acne, vivid dreams, rage, virilization |
| Typical dose reported | 1.5 g / daily | 25 mg / 1 hour before bed |
In summary, there is evidence that n-3 PUFAs supplementation monotherapy improves clinical symptoms and cognitive performances in children and adolescents with ADHD, and that these youth have a deficiency in n-3 PUFAs levels. Our findings provide further support to the rationale for using n-3 PUFAs as a treatment option for ADHD.
Neuropsychopharmacology, 2018 ↗“I have been on the mr.happy stack for about two months(uridine+DHA+choline) and it works wonders for me.”
Vaginal estrogen, vaginal DHEA, oral ospemifene, and vaginal moisturizers may improve some GSM symptoms in the short term. Few long-term data exist on efficacy, comparative effectiveness, tolerability, and safety of GSM treatments.
Ann Intern Med, 2024 ↗“DHEA, minimum 50 mg was a huge game changer for my wife. More energy, libido, dopamine/happy mood, concentration- everything.”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate