Conclusion: The current systematic review and dose-response meta-analysis of RCTs revealed a beneficial effect in both stress and anxiety following Ashwagandha supplementation. However, further high-quality studies are needed to firmly establish the clinical efficacy of the plant.
PubMed 36017529 ↗Ashwagandha
People mainly take Ashwagandha for anxiety, mood, sleep. Based on 961 first-hand reports and 48 meta-analyses & systematic reviews in the medical literature. Ranked #101 of 1,974 overall.
Of reports that state an outcome, 42% are positive.
What Ashwagandha does, according to users
Of the people who reported each effect, the share who said it got better.
7 more with fewer than 3 reports
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: The findings from the included studies indicate that Ashwagandha formulations have beneficial effects on stress and anxiety. The adverse effects associated with Ashwagandha are limited; however, further information is required to determine its safety with long-term administration.
PubMed 39348746 ↗Conclusion: Caffeine enhances attention and executive functions. Together, the results from the compiled studies highlight the nootropic effects and the inconsistencies regarding PDNs that require further research.Supplemental data for this article is available online at https://doi.org/10.1080/10408398.2021.2021137.
PubMed 34978226 ↗Conclusion: Ashwagandha extract appears to has a beneficial effect in improving sleep in adults. However, data on the serious adverse effects of Ashwagandha extract are limited, and more safety data would be needed to assess whether it would be safe for long-term use.
PubMed 34559859 ↗Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“I used to take Ashwagandha daily but stopped.”
“ashwagandha”
“stopped ashwagandha for 2 weeks etc. but nothing worked”
“Boron, Ashwagandha, Creatine + HMB, Multivitamin, and Pre/Post/Pro-biotic fiber gummies.”
“watch how much Ashwagandha you consume and make sure it's KSM-66.”
Other options for anxiety
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate