PlainPill

Ashwagandha vs L-Theanine for anxiety

Short answer: For anxiety, users rate them about the same: 88% report improvement with Ashwagandha (871 reports) and 91% with L-Theanine (1278 reports).

Ashwagandha has 48 meta-analyses and 59 randomized trials on PubMed; L-Theanine has 18 and 78.

Based on 2,426 reports about Ashwagandha and 3,445 about L-Theanine. Not medical advice.

Ashwagandha
Supplement
L-Theanine
Supplement
User score4954
Verdict
Mixed
Mostly positive
Positive
of reports that state an outcome
44%65%
Reports2,4263,445
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs48 / 5918 / 78
Mainly used for
Weight loss
% reporting improvement
100% (3)—
Appetite
% reporting improvement
50% (2)100% (2)
Focus
% reporting improvement
64% (61)88% (496)
Energy
% reporting improvement
53% (124)68% (97)
Sleep
% reporting improvement
77% (230)78% (368)
Anxiety
% reporting improvement
88% (871)91% (1278)
Mood
% reporting improvement
53% (441)77% (222)
Memory
% reporting improvement
75% (8)67% (12)
Performance
% reporting improvement
90% (29)—
Recovery
% reporting improvement
100% (6)—
Pain & inflammation
% reporting improvement
75% (8)100% (5)
Digestion
% reporting improvement
40% (5)—
Libido
% reporting improvement
63% (126)25% (12)
Hormones
% reporting improvement
76% (85)50% (2)
Blood sugar
% reporting improvement
50% (2)—
Heart & lipids
% reporting improvement
50% (6)88% (8)
Skin & hair
% reporting improvement
50% (4)—
Immunity
% reporting improvement
67% (3)100% (2)
Common side effectsanhedonia, drowsiness, anxiety, fatiguedrowsiness, brain fog, vivid dreams, fatigue
Typical dose reporteddaily (past)200 mg / bedtime
Ashwagandha
Latest review conclusion

The current systematic review and dose-response meta-analysis of RCTs revealed a beneficial effect in both stress and anxiety following Ashwagandha supplementation. However, further high-quality studies are needed to firmly establish the clinical efficacy of the plant.

Phytother Res, 2022 ↗
What a user said
“I paired it with maca and ashwaganda and it legit felt like a steroid cycle.”
Full Ashwagandha profile →
L-Theanine
Latest review conclusion

This meta-analysis provides evidence that theanine plus caffeine, and theanine alone, could be beneficial for cognitive and mood outcomes. More research using tea beverages or tea-equivalent bioactive doses and research in free-living participants is needed.

Nutr Rev, 2025 ↗
What a user said
“This morning was my first time taking this combination along with my other daily vitamins and wow, what a difference it has made in my overall mood and anxiety!”
Full L-Theanine profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate