Conclusion: The findings from the included studies indicate that Ashwagandha formulations have beneficial effects on stress and anxiety. The adverse effects associated with Ashwagandha are limited; however, further information is required to determine its safety with long-term administration.
Ashwagandha side effects
Across 2,447 first-hand reports, people mentioned a side effect 318 times (about 13 per 100 reports). The most common: anhedonia, drowsiness, fatigue. User reports show what people notice — they can't tell you whether Ashwagandha is safe for you.
Reported side effects
anhedonia141
drowsiness44
fatigue31
depression26
irritability26
emotional blunting24
apathy14
brain fog12
What got worse for some people
In their own words
“I sleep better. I'm more relaxed. Stress is lower... it caused me terrible depression that lifted once I stopped.”
“My five year old daughter fell beside me and I didn't feel empathy towards her. I stopped taking that shit.”
“Completely believe this. It's literally impossible for me to feel panic/anxiety when I'm fully on Ashwagandha. It's a good life.”
“I've already taken turkesterone, fenugreek, tribulus, and ashwagandha consistently but it didn't have much of an effect to be honest.”
“Ashwagandha is optional and it did not really do a lot for me.”
“I know everyone says if you take ashwagandha for a long period of time it can do that but I've been on a double serving for 3 months and feel the same.”
Is Ashwagandha safe? What the research covers
AResearch: Strong48 meta-analyses · 59 randomized trials on PubMed
Explore (NY) · 2024
Effects of Ashwagandha (Withania Somnifera) on stress and anxiety: A systematic review and meta-analysisPLoS One · 2021
Effect of Ashwagandha (Withania somnifera) extract on sleep: A systematic review and meta-analysisConclusion: Ashwagandha extract appears to has a beneficial effect in improving sleep in adults. However, data on the serious adverse effects of Ashwagandha extract are limited, and more safety data would be needed to assess whether it would be safe for long-term use.