Best for anxiety

324 options people report for stress, calm and social anxiety, ranked by the share of users who say it improved — weighted by how many reports there are.

Weight loss Appetite Focus Energy Sleep Anxiety Mood Memory Performance Recovery Pain & inflammation Digestion Libido Hormones Blood sugar Heart & lipids Skin & hair Immunity Longevity

Type:All Supplements Peptides Medications Substances Lifestyle Methods SARMs OtherResearch-backed only

50 results

149

PropranololMedication

Anxiety Sleep Focus

97% report better Anxiety

35 reports

Mostly positiveAResearch: Strong

241

TianeptineMedication

Mood Anxiety Focus

93% report better Anxiety

15 reports

MixedAResearch: Strong

331

GabapentinMedication

Anxiety Sleep Mood

80% report better Anxiety

20 reports

MixedAResearch: Strong

450

XanaxMedication

Anxiety Sleep Focus

82% report better Anxiety

17 reports

MixedBResearch: Moderate

545

TestosteroneMedication

Performance Mood Libido

81% report better Anxiety

16 reports

Mostly positiveAResearch: Strong

646

MemantineMedication

Mood Focus Anxiety

91% report better Anxiety

11 reports

MixedAResearch: Strong

734

BaclofenMedication

Anxiety Mood Sleep

100% report better Anxiety

8 reports

Mostly positiveAResearch: Strong

857

GuanfacineMedication

Focus Anxiety Sleep

100% report better Anxiety

7 reports

Mostly positiveAResearch: Strong

936

LexaproMedication

Mood Anxiety Libido

78% report better Anxiety

9 reports

MixedBResearch: Moderate

1027

EtifoxineMedication

Anxiety

100% report better Anxiety

5 reports

Mostly positiveBResearch: Moderate

1125

LorazepamMedication

Anxiety

100% report better Anxiety

5 reports

MixedAResearch: Strong

1222

BuspironeMedication

Anxiety Mood

75% report better Anxiety

8 reports

MixedAResearch: Strong

1331

ZoloftMedication

Mood Anxiety Energy

83% report better Anxiety

6 reports

Mostly positiveBResearch: Moderate

1428

FluoxetineMedication

Mood Anxiety Energy

83% report better Anxiety

6 reports

MixedAResearch: Strong

1524

SertralineMedication

Anxiety Mood

83% report better Anxiety

6 reports

MixedAResearch: Strong

1634

ClonazepamMedication

Anxiety Focus Energy

100% report better Anxiety

4 reports

MixedAResearch: Strong

1726

AtivanMedication

Anxiety Sleep

100% report better Anxiety

4 reports

Mostly positiveAResearch: Strong

1819

EffexorMedication

Anxiety Mood

100% report better Anxiety

4 reports

MixedBResearch: Moderate

1932

MethylphenidateMedication

Focus Mood Anxiety

58% report better Anxiety

12 reports

MixedAResearch: Strong

2021

PregabalinMedication

Anxiety Mood Memory

71% report better Anxiety

7 reports

MixedAResearch: Strong

2147

TRTMedication

Mood Energy Hormones

80% report better Anxiety

5 reports

Mostly positiveAResearch: Strong

2236

KetamineMedication

Mood Anxiety Heart & lipids

80% report better Anxiety

5 reports

MixedAResearch: Strong

2324

ProzacMedication

Mood Anxiety Libido

100% report better Anxiety

3 reports

MixedAResearch: Strong

2422

Intranasal InsulinMedication

Focus Memory Energy

100% report better Anxiety

3 reports

MixedAResearch: Strong

2519

ClonidineMedication

Anxiety Sleep Mood

100% report better Anxiety

3 reports

MixedAResearch: Strong

2619

Beta BlockersMedication

Anxiety Sleep

75% report better Anxiety

4 reports

Mostly positiveAResearch: Strong

2729

EscitalopramMedication

Mood Anxiety Energy

57% report better Anxiety

7 reports

MixedAResearch: Strong

2862

TadalafilMedication

Libido Performance Mood

100% report better Anxiety

2 reports

Mostly positiveAResearch: Strong

2941

ArmodafinilMedication

Focus Energy Mood

100% report better Anxiety

2 reports

Mostly positiveAResearch: Strong

3031

Low Dose NaltrexoneMedication

Focus Energy Mood

100% report better Anxiety

2 reports

Mostly positiveAResearch: Strong

3130

MirtazapineMedication

Sleep Mood Anxiety

100% report better Anxiety

2 reports

MixedAResearch: Strong

3225

HydroxyzineMedication

Sleep Anxiety

100% report better Anxiety

2 reports

MixedAResearch: Strong

3319

Ketamine TherapyMedication

Mood Anxiety

100% report better Anxiety

2 reports

Mostly positiveBResearch: Moderate

3414

AlprazolamMedication

Anxiety Focus Sleep

100% report better Anxiety

2 reports

MixedAResearch: Strong

3514

DiazepamMedication

Anxiety Sleep

100% report better Anxiety

2 reports

Mostly negativeAResearch: Strong

3614

Ketamine InfusionsMedication

Anxiety Mood

100% report better Anxiety

2 reports

MixedAResearch: Strong

3743

SelegilineMedication

Mood Focus Energy

50% report better Anxiety

6 reports

MixedAResearch: Strong

3853

AdderallMedication

Focus Mood Energy

28% report better Anxiety

29 reports

MixedAResearch: Strong

3914

EtizolamMedication

Anxiety Focus Sleep

67% report better Anxiety

3 reports

Mostly negativeBResearch: Moderate

4054

WellbutrinMedication

Mood Energy Focus

50% report better Anxiety

4 reports

MixedBResearch: Moderate

4128

BenadrylMedication

Sleep Anxiety Focus

50% report better Anxiety

4 reports

MixedBResearch: Moderate

4236

VyvanseMedication

Focus Mood Energy

29% report better Anxiety

14 reports

MixedBResearch: Moderate

4346

ModafinilMedication

Focus Energy Mood

21% report better Anxiety

33 reports

MixedAResearch: Strong

4424

VortioxetineMedication

Mood Memory Energy

50% report better Anxiety

2 reports

MixedAResearch: Strong

4538

BupropionMedication

Mood Energy Focus

22% report better Anxiety

9 reports

MixedAResearch: Strong

4631

ConcertaMedication

Focus Energy Anxiety

33% report better Anxiety

3 reports

MixedBResearch: Moderate

4722

VenlafaxineMedication

Anxiety Focus

33% report better Anxiety

3 reports

Mostly negativeAResearch: Strong

4829

RitalinMedication

Focus Mood Anxiety

18% report better Anxiety

11 reports

MixedAResearch: Strong

4949

FinasterideMedication

Skin & hair Libido Mood

0% report better Anxiety

3 reports

MixedAResearch: Strong

5025

Adderall XrMedication

Focus Mood Energy

0% report better Anxiety

2 reports

MixedBResearch: Moderate

Minimum 2 reports per entry. Information only — not medical advice. How rankings work