LGD-4033 vs MK-677 for performance
Short answer: For performance, users rate them about the same: 90% report improvement with LGD-4033 (178 reports) and 88% with MK-677 (68 reports).
LGD-4033 has 1 meta-analyses and 1 randomized trials on PubMed; MK-677 has 0 and 15.
Based on 491 reports about LGD-4033 and 692 about MK-677. Not medical advice.
| LGD-4033 SARM | MK-677 Substance | |
|---|---|---|
| User score | 54 | 45 |
| Verdict | Mixed | Mixed |
| Positive of reports that state an outcome | 50% | 41% |
| Reports | 491 | 692 |
| Research | BResearch: Moderate | BResearch: Moderate |
| Meta-analyses / RCTs | 1 / 1 | 0 / 15 |
| Mainly used for | ||
| Weight loss % reporting improvement | 94% (33) | 63% (43) |
| Appetite % reporting improvement | 60% (5) | 62% (152) |
| Focus % reporting improvement | 50% (4) | 0% (3) |
| Energy % reporting improvement | 45% (22) | 39% (49) |
| Sleep % reporting improvement | 17% (6) | 78% (123) |
| Anxiety % reporting improvement | 0% (3) | 5% (21) |
| Mood % reporting improvement | 25% (24) | 59% (17) |
| Performance % reporting improvement | 90% (178) | 88% (68) |
| Recovery % reporting improvement | 100% (13) | 99% (81) |
| Pain & inflammation % reporting improvement | 0% (5) | 67% (18) |
| Digestion % reporting improvement | 50% (2) | 50% (2) |
| Libido % reporting improvement | 19% (27) | 25% (8) |
| Hormones % reporting improvement | 4% (48) | 41% (34) |
| Blood sugar % reporting improvement | — | 5% (44) |
| Heart & lipids % reporting improvement | 0% (12) | 8% (12) |
| Skin & hair % reporting improvement | 0% (3) | 92% (24) |
| Common side effects | suppression, water retention, fatigue, stomach issues | water retention, fatigue, hunger, stomach issues |
| Typical dose reported | Not listed | 12.5 mg / before dinner |
LGD-4033Full LGD-4033 profile →
Latest review conclusion
SARMs have a positive effect on physical performance and body composition and are associated with moderate rates of mild to moderate adverse effects (AEs) and a low rate of severe AEs.
Clin Endocrinol (Oxf), 2025 ↗What a user said
“I've taken LDG-4033 and Ostarine from Ceretropic and noticed slight psychoactive effects from both, immediately (within 30 minutes after dosing).”
MK-677Full MK-677 profile →
What a user said
“From my own experience (also have suffered from poor sleep), i experienced a noticeable increase in sleep quality even with a low dose.”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate