MK-677
People mainly take MK-677 for sleep, performance, recovery. Based on 168 first-hand reports and 0 meta-analyses & systematic reviews in the medical literature. Ranked #90 of 1,974 overall.
Of reports that state an outcome, 51% are positive.
What MK-677 does, according to users
Of the people who reported each effect, the share who said it got better.
What the research says
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.
Dosage people report
As stated by users — not a recommendation. Follow the label or your doctor.
Reported side effects
How often each side effect came up across all reports.
What users say
Verbatim quotes, shortened only — each links to the original discussion.
“Mk 677 apparently increases HGH levels comparable to around 2 IU's of generics”
“ive heard the latter may lead to heart complications”
“Mk-677”
“Noticed enhanced recovery, muscle fullness, better skin, and increased hunger.”
“it shines when it comes to recovery and it helps keeping you from going catabolic. I lost stomach fat on it and have had less joint pain from tendinosis”
Other options for sleep
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate