GW-501516 vs LGD-4033 for performance
Short answer: For performance, users rate them about the same: 93% report improvement with GW-501516 (71 reports) and 91% with LGD-4033 (175 reports).
GW-501516 has 0 meta-analyses and 0 randomized trials on PubMed; LGD-4033 has 1 and 1.
Based on 307 reports about GW-501516 and 485 about LGD-4033. Not medical advice.
| GW-501516 Substance | LGD-4033 SARM | |
|---|---|---|
| User score | 46 | 54 |
| Verdict | Mostly positive | Mixed |
| Positive of reports that state an outcome | 64% | 51% |
| Reports | 307 | 485 |
| Research | DResearch: None | BResearch: Moderate |
| Meta-analyses / RCTs | 0 / 0 | 1 / 1 |
| Mainly used for | ||
| Weight loss % reporting improvement | 86% (50) | 94% (32) |
| Appetite % reporting improvement | 50% (4) | 60% (5) |
| Focus % reporting improvement | — | 50% (4) |
| Energy % reporting improvement | 95% (19) | 43% (21) |
| Sleep % reporting improvement | 0% (2) | 17% (6) |
| Anxiety % reporting improvement | — | 0% (3) |
| Mood % reporting improvement | 100% (2) | 22% (23) |
| Performance % reporting improvement | 93% (71) | 91% (175) |
| Recovery % reporting improvement | 100% (3) | 100% (13) |
| Pain & inflammation % reporting improvement | — | 0% (5) |
| Digestion % reporting improvement | — | 50% (2) |
| Libido % reporting improvement | — | 19% (27) |
| Hormones % reporting improvement | — | 4% (48) |
| Heart & lipids % reporting improvement | 89% (19) | 0% (12) |
| Skin & hair % reporting improvement | — | 0% (3) |
| Longevity % reporting improvement | 50% (2) | — |
| Common side effects | cancer risk, acne, fatigue, brain fog | suppression, water retention, fatigue, stomach issues |
| Typical dose reported | 20 mg | Not listed |
LGD-4033Full LGD-4033 profile →
Latest review conclusion
SARMs have a positive effect on physical performance and body composition and are associated with moderate rates of mild to moderate adverse effects (AEs) and a low rate of severe AEs.
Clin Endocrinol (Oxf), 2025 ↗What a user said
“SARMs suck dick.”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate