LGD-4033 vs MK-2866 for performance
Short answer: For performance, users rate them about the same: 90% report improvement with LGD-4033 (178 reports) and 88% with MK-2866 (192 reports).
LGD-4033 has 1 meta-analyses and 1 randomized trials on PubMed; MK-2866 has 0 and 0.
Based on 491 reports about LGD-4033 and 612 about MK-2866. Not medical advice.
| LGD-4033 SARM | MK-2866 SARM | |
|---|---|---|
| User score | 54 | 33 |
| Verdict | Mixed | Mixed |
| Positive of reports that state an outcome | 50% | 39% |
| Reports | 491 | 612 |
| Research | BResearch: Moderate | DResearch: None |
| Meta-analyses / RCTs | 1 / 1 | 0 / 0 |
| Mainly used for | ||
| Weight loss % reporting improvement | 94% (33) | 89% (80) |
| Appetite % reporting improvement | 60% (5) | 62% (8) |
| Focus % reporting improvement | 50% (4) | 71% (7) |
| Energy % reporting improvement | 45% (22) | 54% (37) |
| Sleep % reporting improvement | 17% (6) | 20% (20) |
| Anxiety % reporting improvement | 0% (3) | 33% (9) |
| Mood % reporting improvement | 25% (24) | 63% (49) |
| Performance % reporting improvement | 90% (178) | 88% (192) |
| Recovery % reporting improvement | 100% (13) | 97% (60) |
| Pain & inflammation % reporting improvement | 0% (5) | 70% (27) |
| Digestion % reporting improvement | 50% (2) | — |
| Libido % reporting improvement | 19% (27) | 31% (45) |
| Hormones % reporting improvement | 4% (48) | 4% (82) |
| Heart & lipids % reporting improvement | 0% (12) | 0% (8) |
| Skin & hair % reporting improvement | 0% (3) | 33% (6) |
| Common side effects | suppression, water retention, fatigue, stomach issues | suppression, fatigue, insomnia, headache |
| Typical dose reported | Not listed | Not listed |
LGD-4033Full LGD-4033 profile →
Latest review conclusion
SARMs have a positive effect on physical performance and body composition and are associated with moderate rates of mild to moderate adverse effects (AEs) and a low rate of severe AEs.
Clin Endocrinol (Oxf), 2025 ↗What a user said
“I've taken LDG-4033 and Ostarine from Ceretropic and noticed slight psychoactive effects from both, immediately (within 30 minutes after dosing).”
MK-2866Full MK-2866 profile →
What a user said
“I've taken LDG-4033 and Ostarine from Ceretropic and noticed slight psychoactive effects from both, immediately (within 30 minutes after dosing).”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate