People mainly take LGD-4033 for performance, hormones, recovery. Based on 125 first-hand reports and 1 meta-analyses & systematic reviews in the medical literature. Ranked #36 of 1,974 overall.
Of reports that state an outcome, 57% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
At least one meta-analysis, or 5+ randomized controlled trials. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: SARMs have a positive effect on physical performance and body composition and are associated with moderate rates of mild to moderate adverse effects (AEs) and a low rate of severe AEs.
PubMed 39285652 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“SARMs suck dick.”
“Steroids : lgd4033 & enclomiphene”
“I performed a GC-MS analysis on Swiss Pharmaceuticals Mk-777 and found the typical fragmentation pattern for LGD-4033”
“LGD-4033 is the more potent one that needs a PCT.”
“LGD-4033 really helps with cognition ... More creative thinking, confidence and better sleep”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate