Creatine vs LGD-4033 for performance
Short answer: For performance, more users report improvement with Creatine — 97% of 320 reports, versus 90% of 178 for LGD-4033.
Creatine has 763 meta-analyses and 2,794 randomized trials on PubMed; LGD-4033 has 1 and 1.
Based on 1,564 reports about Creatine and 491 about LGD-4033. Not medical advice.
| Creatine Supplement | LGD-4033 SARM | |
|---|---|---|
| User score | 53 | 54 |
| Verdict | Mostly positive | Mixed |
| Positive of reports that state an outcome | 67% | 50% |
| Reports | 1,564 | 491 |
| Research | AResearch: Strong | BResearch: Moderate |
| Meta-analyses / RCTs | 763 / 2,794 | 1 / 1 |
| Mainly used for | ||
| Weight loss % reporting improvement | 82% (11) | 94% (33) |
| Appetite % reporting improvement | 67% (3) | 60% (5) |
| Focus % reporting improvement | 92% (211) | 50% (4) |
| Energy % reporting improvement | 97% (205) | 45% (22) |
| Sleep % reporting improvement | 27% (73) | 17% (6) |
| Anxiety % reporting improvement | 62% (24) | 0% (3) |
| Mood % reporting improvement | 85% (103) | 25% (24) |
| Memory % reporting improvement | 91% (70) | — |
| Performance % reporting improvement | 97% (320) | 90% (178) |
| Recovery % reporting improvement | 98% (62) | 100% (13) |
| Pain & inflammation % reporting improvement | 50% (4) | 0% (5) |
| Digestion % reporting improvement | 0% (6) | 50% (2) |
| Libido % reporting improvement | 82% (11) | 19% (27) |
| Hormones % reporting improvement | 75% (12) | 4% (48) |
| Blood sugar % reporting improvement | 100% (3) | — |
| Heart & lipids % reporting improvement | 67% (6) | 0% (12) |
| Skin & hair % reporting improvement | 17% (12) | 0% (3) |
| Longevity % reporting improvement | 100% (4) | — |
| Common side effects | hair loss, stomach issues, insomnia, water retention | suppression, water retention, fatigue, stomach issues |
| Typical dose reported | daily | Not listed |
The results of the meta-analysis suggest that creatine supplementation did not significantly alter serum creatinine levels (standardized mean difference = 0.48, 95% confidence interval 0.24-0.73, P = .001, I2 = 22%), and did not alter plasma urea values (standardized mean difference = 1.10, 95% confidence interval 0.34-1.85, P = .004, I2 = 28%). The findings indicate that creatine supplementation does not induce renal damage in the studied amounts and durations.
J Ren Nutr, 2019 ↗“I actually feel a lot better. Mentally clearer and more balanced, like I have my brain back.”
SARMs have a positive effect on physical performance and body composition and are associated with moderate rates of mild to moderate adverse effects (AEs) and a low rate of severe AEs.
Clin Endocrinol (Oxf), 2025 ↗“I've taken LDG-4033 and Ostarine from Ceretropic and noticed slight psychoactive effects from both, immediately (within 30 minutes after dosing).”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate