MK-677 vs Testosterone for performance
Short answer: For performance, more users report improvement with Testosterone — 97% of 149 reports, versus 88% of 68 for MK-677.
MK-677 has 0 meta-analyses and 15 randomized trials on PubMed; Testosterone has 75 and 125.
Based on 692 reports about MK-677 and 822 about Testosterone. Not medical advice.
| MK-677 Substance | Testosterone Medication | |
|---|---|---|
| User score | 45 | 54 |
| Verdict | Mixed | Mostly positive |
| Positive of reports that state an outcome | 41% | 77% |
| Reports | 692 | 822 |
| Research | BResearch: Moderate | AResearch: Strong |
| Meta-analyses / RCTs | 0 / 15 | 75 / 125 |
| Mainly used for | ||
| Weight loss % reporting improvement | 63% (43) | 93% (45) |
| Appetite % reporting improvement | 62% (152) | — |
| Focus % reporting improvement | 0% (3) | 82% (28) |
| Energy % reporting improvement | 39% (49) | 92% (76) |
| Sleep % reporting improvement | 78% (123) | 79% (19) |
| Anxiety % reporting improvement | 5% (21) | 80% (25) |
| Mood % reporting improvement | 59% (17) | 88% (104) |
| Memory % reporting improvement | — | 100% (2) |
| Performance % reporting improvement | 88% (68) | 97% (149) |
| Recovery % reporting improvement | 99% (81) | 91% (23) |
| Pain & inflammation % reporting improvement | 67% (18) | 67% (6) |
| Digestion % reporting improvement | 50% (2) | — |
| Libido % reporting improvement | 25% (8) | 93% (70) |
| Hormones % reporting improvement | 41% (34) | 90% (91) |
| Blood sugar % reporting improvement | 5% (44) | — |
| Heart & lipids % reporting improvement | 8% (12) | 62% (8) |
| Skin & hair % reporting improvement | 92% (24) | 40% (5) |
| Longevity % reporting improvement | — | 50% (2) |
| Common side effects | water retention, fatigue, hunger, stomach issues | suppression, hair loss, acne, water retention |
| Typical dose reported | 12.5 mg / before dinner | 200 mg / weekly |
MK-677Full MK-677 profile →
What a user said
“From my own experience (also have suffered from poor sleep), i experienced a noticeable increase in sleep quality even with a low dose.”
TestosteroneFull Testosterone profile →
Latest review conclusion
The guidelines also provide recommendations regarding identification of patients, dosing, monitoring, and follow-up. This Practice Pearl will discuss evidence-based testosterone therapy for management of HSDD in postmenopausal women.
Menopause, 2023 ↗What a user said
“Feel the best I've ever felt in my life. TRT and peptides have been game changers for me!”
Related comparisons
Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate