Agmatine vs Tyrosine for mood
Short answer: For mood, users rate them about the same: 87% report improvement with Agmatine (122 reports) and 83% with Tyrosine (160 reports).
Agmatine has 2 meta-analyses and 6 randomized trials on PubMed; Tyrosine has 2,190 and 1,766.
Based on 594 reports about Agmatine and 1,154 about Tyrosine. Not medical advice.
| Agmatine Supplement | Tyrosine Supplement | |
|---|---|---|
| User score | 55 | 47 |
| Verdict | Mostly positive | Mixed |
| Positive of reports that state an outcome | 68% | 56% |
| Reports | 594 | 1,154 |
| Research | BResearch: Moderate | AResearch: Strong |
| Meta-analyses / RCTs | 2 / 6 | 2,190 / 1,766 |
| Mainly used for | ||
| Appetite % reporting improvement | 88% (8) | — |
| Focus % reporting improvement | 67% (24) | 82% (206) |
| Energy % reporting improvement | 65% (23) | 89% (152) |
| Sleep % reporting improvement | 79% (34) | 30% (10) |
| Anxiety % reporting improvement | 89% (93) | 60% (40) |
| Mood % reporting improvement | 87% (122) | 83% (160) |
| Memory % reporting improvement | 75% (4) | 78% (9) |
| Performance % reporting improvement | 96% (26) | 100% (8) |
| Recovery % reporting improvement | 100% (2) | — |
| Pain & inflammation % reporting improvement | 88% (16) | 50% (4) |
| Libido % reporting improvement | 100% (10) | 75% (12) |
| Hormones % reporting improvement | 50% (2) | 100% (6) |
| Heart & lipids % reporting improvement | 80% (5) | — |
| Skin & hair % reporting improvement | — | 67% (6) |
| Immunity % reporting improvement | — | 100% (2) |
| Common side effects | drowsiness, vivid dreams, anxiety, stomach issues | anxiety, insomnia, jitteriness, headache |
| Typical dose reported | 1.5 g / before workout | 500 mg / daily |
Levels of food-derived monoamine oxidase inhibitors and anti-bacterial compounds, the potential modulators of ADAS-bacteria growth and biogenic amine production, were altered in C&A versus NNI. ADAS is attributable to potentially modifiable risk factors of AD associated diseases.
J Alzheimers Dis, 2019 ↗“Try using agimatine sulfate. when I took kratom for five years for pain management this is what I used to keep my tolerance in check and feeling like I've used it for the first time every time.”
In patients with EGFR-mutated NSCLC, first and third generation EGFR tyrosine kinase inhibitors, as well as combination therapies with antiangiogenesis, were associated with increased risks of cardiovascular adverse events. Risks were significantly higher with third generation compared with first generation inhibitors.
BMJ, 2025 ↗“I stack taurine with tyrosine and creatine and that has helped my mood noticeably and also helps me feel stronger and more energetic.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate