PlainPill

Agmatine vs Exercise for mood

Short answer: For mood, more users report improvement with Exercise — 95% of 187 reports, versus 87% of 122 for Agmatine.

Agmatine has 2 meta-analyses and 6 randomized trials on PubMed; the other has not been graded.

Based on 594 reports about Agmatine and 738 about Exercise. Not medical advice.

Agmatine
Supplement
Exercise
Lifestyle
User score5563
Verdict
Mostly positive
Mostly positive
Positive
of reports that state an outcome
68%89%
Reports594738
ResearchBResearch: ModerateResearch pending
Meta-analyses / RCTs2 / 6—
Mainly used for
Weight loss
% reporting improvement
—100% (10)
Appetite
% reporting improvement
88% (8)100% (3)
Focus
% reporting improvement
67% (24)95% (66)
Energy
% reporting improvement
65% (23)90% (88)
Sleep
% reporting improvement
79% (34)96% (51)
Anxiety
% reporting improvement
89% (93)95% (93)
Mood
% reporting improvement
87% (122)95% (187)
Memory
% reporting improvement
75% (4)100% (8)
Performance
% reporting improvement
96% (26)100% (28)
Recovery
% reporting improvement
100% (2)100% (3)
Pain & inflammation
% reporting improvement
88% (16)100% (3)
Digestion
% reporting improvement
—100% (2)
Libido
% reporting improvement
100% (10)94% (18)
Hormones
% reporting improvement
50% (2)100% (14)
Blood sugar
% reporting improvement
—100% (2)
Heart & lipids
% reporting improvement
80% (5)85% (13)
Skin & hair
% reporting improvement
—100% (3)
Immunity
% reporting improvement
—100% (6)
Longevity
% reporting improvement
—100% (9)
Common side effectsdrowsiness, vivid dreams, anxiety, stomach issuesfatigue, insomnia, initial fatigue
Typical dose reported1.5 g / before workoutmultiple times a week
Agmatine
Latest review conclusion

Levels of food-derived monoamine oxidase inhibitors and anti-bacterial compounds, the potential modulators of ADAS-bacteria growth and biogenic amine production, were altered in C&A versus NNI. ADAS is attributable to potentially modifiable risk factors of AD associated diseases.

J Alzheimers Dis, 2019 ↗
What a user said
“Try using agimatine sulfate. when I took kratom for five years for pain management this is what I used to keep my tolerance in check and feeling like I've used it for the first time every time.”
Full Agmatine profile →
Exercise
What a user said
“nothing has improved my mental health like daily and difficult physical exercise has.”
Full Exercise profile →

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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate