Creatine vs Tyrosine for energy
Short answer: For energy, more users report improvement with Creatine — 97% of 205 reports, versus 89% of 152 for Tyrosine.
Creatine has 763 meta-analyses and 2,794 randomized trials on PubMed; Tyrosine has 2,190 and 1,766.
Based on 1,564 reports about Creatine and 1,154 about Tyrosine. Not medical advice.
| Creatine Supplement | Tyrosine Supplement | |
|---|---|---|
| User score | 53 | 47 |
| Verdict | Mostly positive | Mixed |
| Positive of reports that state an outcome | 67% | 56% |
| Reports | 1,564 | 1,154 |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 763 / 2,794 | 2,190 / 1,766 |
| Mainly used for | ||
| Weight loss % reporting improvement | 82% (11) | — |
| Appetite % reporting improvement | 67% (3) | — |
| Focus % reporting improvement | 92% (211) | 82% (206) |
| Energy % reporting improvement | 97% (205) | 89% (152) |
| Sleep % reporting improvement | 27% (73) | 30% (10) |
| Anxiety % reporting improvement | 62% (24) | 60% (40) |
| Mood % reporting improvement | 85% (103) | 83% (160) |
| Memory % reporting improvement | 91% (70) | 78% (9) |
| Performance % reporting improvement | 97% (320) | 100% (8) |
| Recovery % reporting improvement | 98% (62) | — |
| Pain & inflammation % reporting improvement | 50% (4) | 50% (4) |
| Digestion % reporting improvement | 0% (6) | — |
| Libido % reporting improvement | 82% (11) | 75% (12) |
| Hormones % reporting improvement | 75% (12) | 100% (6) |
| Blood sugar % reporting improvement | 100% (3) | — |
| Heart & lipids % reporting improvement | 67% (6) | — |
| Skin & hair % reporting improvement | 17% (12) | 67% (6) |
| Immunity % reporting improvement | — | 100% (2) |
| Longevity % reporting improvement | 100% (4) | — |
| Common side effects | hair loss, stomach issues, insomnia, water retention | anxiety, insomnia, jitteriness, headache |
| Typical dose reported | daily | 500 mg / daily |
The results of the meta-analysis suggest that creatine supplementation did not significantly alter serum creatinine levels (standardized mean difference = 0.48, 95% confidence interval 0.24-0.73, P = .001, I2 = 22%), and did not alter plasma urea values (standardized mean difference = 1.10, 95% confidence interval 0.34-1.85, P = .004, I2 = 28%). The findings indicate that creatine supplementation does not induce renal damage in the studied amounts and durations.
J Ren Nutr, 2019 ↗“I actually feel a lot better. Mentally clearer and more balanced, like I have my brain back.”
In patients with EGFR-mutated NSCLC, first and third generation EGFR tyrosine kinase inhibitors, as well as combination therapies with antiangiogenesis, were associated with increased risks of cardiovascular adverse events. Risks were significantly higher with third generation compared with first generation inhibitors.
BMJ, 2025 ↗“I stack taurine with tyrosine and creatine and that has helped my mood noticeably and also helps me feel stronger and more energetic.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate