Agmatine vs Saffron for mood
Short answer: For mood, more users report improvement with Saffron — 92% of 123 reports, versus 87% of 122 for Agmatine.
Agmatine has 2 meta-analyses and 6 randomized trials on PubMed; Saffron has 88 and 119.
Based on 594 reports about Agmatine and 323 about Saffron. Not medical advice.
| Agmatine Supplement | Saffron Supplement | |
|---|---|---|
| User score | 55 | 58 |
| Verdict | Mostly positive | Mostly positive |
| Positive of reports that state an outcome | 68% | 64% |
| Reports | 594 | 323 |
| Research | BResearch: Moderate | AResearch: Strong |
| Meta-analyses / RCTs | 2 / 6 | 88 / 119 |
| Mainly used for | ||
| Appetite % reporting improvement | 88% (8) | 80% (10) |
| Focus % reporting improvement | 67% (24) | 80% (30) |
| Energy % reporting improvement | 65% (23) | 78% (18) |
| Sleep % reporting improvement | 79% (34) | 77% (13) |
| Anxiety % reporting improvement | 89% (93) | 80% (75) |
| Mood % reporting improvement | 87% (122) | 92% (123) |
| Memory % reporting improvement | 75% (4) | 50% (2) |
| Performance % reporting improvement | 96% (26) | — |
| Recovery % reporting improvement | 100% (2) | — |
| Pain & inflammation % reporting improvement | 88% (16) | 100% (3) |
| Digestion % reporting improvement | — | 50% (2) |
| Libido % reporting improvement | 100% (10) | 75% (12) |
| Hormones % reporting improvement | 50% (2) | — |
| Heart & lipids % reporting improvement | 80% (5) | 50% (2) |
| Common side effects | drowsiness, vivid dreams, anxiety, stomach issues | headache, anxiety, appetite suppression, vivid dreams |
| Typical dose reported | 1.5 g / before workout | daily, morning |
Levels of food-derived monoamine oxidase inhibitors and anti-bacterial compounds, the potential modulators of ADAS-bacteria growth and biogenic amine production, were altered in C&A versus NNI. ADAS is attributable to potentially modifiable risk factors of AD associated diseases.
J Alzheimers Dis, 2019 ↗“Try using agimatine sulfate. when I took kratom for five years for pain management this is what I used to keep my tolerance in check and feeling like I've used it for the first time every time.”
Saffron demonstrates promise in improving ADHD symptoms, with an acceptable safety profile. Future well-designed multicentral studies are suggested.
J Atten Disord, 2024 ↗“I just sneak some into whatever soup we are having. I honestly think it has made a huge difference.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate