Caffeine vs Tyrosine for energy
Short answer: For energy, more users report improvement with Tyrosine — 89% of 152 reports, versus 78% of 540 for Caffeine.
Caffeine has 680 meta-analyses and 2,072 randomized trials on PubMed; Tyrosine has 2,190 and 1,766.
Based on 1,607 reports about Caffeine and 1,154 about Tyrosine. Not medical advice.
| Caffeine Substance | Tyrosine Supplement | |
|---|---|---|
| User score | 49 | 47 |
| Verdict | Mixed | Mixed |
| Positive of reports that state an outcome | 42% | 56% |
| Reports | 1,607 | 1,154 |
| Research | AResearch: Strong | AResearch: Strong |
| Meta-analyses / RCTs | 680 / 2,072 | 2,190 / 1,766 |
| Mainly used for | ||
| Weight loss % reporting improvement | 90% (10) | — |
| Appetite % reporting improvement | 67% (6) | — |
| Focus % reporting improvement | 79% (368) | 82% (206) |
| Energy % reporting improvement | 78% (540) | 89% (152) |
| Sleep % reporting improvement | 14% (112) | 30% (10) |
| Anxiety % reporting improvement | 16% (210) | 60% (40) |
| Mood % reporting improvement | 73% (110) | 83% (160) |
| Memory % reporting improvement | 53% (19) | 78% (9) |
| Performance % reporting improvement | 91% (35) | 100% (8) |
| Pain & inflammation % reporting improvement | 40% (5) | 50% (4) |
| Digestion % reporting improvement | 29% (7) | — |
| Libido % reporting improvement | 0% (2) | 75% (12) |
| Hormones % reporting improvement | 25% (4) | 100% (6) |
| Heart & lipids % reporting improvement | 8% (12) | — |
| Skin & hair % reporting improvement | — | 67% (6) |
| Immunity % reporting improvement | — | 100% (2) |
| Common side effects | jitteriness, anxiety, insomnia, headache | anxiety, insomnia, jitteriness, headache |
| Typical dose reported | 100-150 mg / daily | 500 mg / daily |
To avoid reductions in total sleep time, coffee (107 mg per 250 mL) should be consumed at least 8.8 h prior to bedtime and a standard serve of pre-workout supplement (217.5 mg) should be consumed at least 13.2 h prior to bedtime. The results of the present study provide evidence-based guidance for the appropriate consumption of caffeine to mitigate the deleterious effects on sleep.
Sleep Med Rev, 2023 ↗“Personally, I feel and function much better if I keep my caffeine intake very low to zero.”
In patients with EGFR-mutated NSCLC, first and third generation EGFR tyrosine kinase inhibitors, as well as combination therapies with antiangiogenesis, were associated with increased risks of cardiovascular adverse events. Risks were significantly higher with third generation compared with first generation inhibitors.
BMJ, 2025 ↗“I stack taurine with tyrosine and creatine and that has helped my mood noticeably and also helps me feel stronger and more energetic.”
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Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate