PlainPill

What people actually say

4,893 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
“Berberine has done zero for my pre diabetic glucose levels or weight. Metformin has and I changed nothing else.”
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“2 days with Metformin and that’s gone. I feel like I did when i was in my 30’s.”
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“Metformin (2 months, hoping to reduce hunger or increase energy), and there is way many more and others I can't remember.”
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Magnesium OxideMostly negative
“The next day, my legs felt amazing. I could walk again without feeling like my legs were deadweight.”
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Magnesium OxideMostly negative
“I've tried various forms of magnesium over the past year including threonate, glycinate, citrate, oxide, and taurate. They all give the same negative side effects.”
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Magnesium OxideMostly negative
“Oxide has shit bioavailability but that didn't bother unless I too ka fairly large dose, it's basically a diuretic.”
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Magnesium OxideMostly negative
“I feel emotionally blunted when I take magnesium during the day, but it's great at night.”
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“i find valarian helps me stay asleep, if you can get past the smell.”
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“I then tried raising GABA instead, using Valerian, Passion Flower, L-Theanine etc. All at max dosage, no effect whatsoever.”
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“For years I struggled with post workout insomnia. PS along with valerian helped.”
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“Valerian/chamomile (also calm, but not as much, chamomile in particular seems to be amazing when im actually very stressed out but not much otherwise)”
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Magnesium MalateMostly positive
“malate is a much better option for me (though stil gives me some energy, just not the panic/sense of dread that glycinate does)”
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Magnesium MalateMostly positive
“Malate and bisglycinate have worked best for me as they are more energizing and bioavailable forms.”
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Magnesium MalateMostly positive
“Magnesium malate seems to work the best for me...Malate improves energy production in mitochondria.”
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Magnesium MalateMostly positive
“Magnesium malate is the energizing kind of mag, glycinate I would only take in the evening for better sleep (which will give you more energy in a roundabout way).”
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CBD OilMixed
“CBD oil (this is very personal, but for me, it seems to work to get into deeper sleep)”
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CBD OilMixed
“usual recommendations: CBD oil, ashwaghanda, valerian, lemon balm, theanine, GABA and about a half dozen others. Ashwaghanda helped with my stress and levels and lemon balm and theanine had a mild effect but that's about it.”
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CBD OilMixed
“Within 20 minutes I could feel a softness gradually washing over my brain. It was incredibly gentle and soft as if the CBD was telling me everything was going to be okay.”
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CBD OilMixed
“Probably most notable for anxiety and the cognitive benefits that come from treating the anxiety like other nootropics. I also believe it has anti-inflammatory properties too.”
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PropranololMostly positive
“I just got a script for propranolol that I can take as needed and it's been a game changer.”
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PropranololMostly positive
“Minimal decrease in anxiety but I am pretty sure that it only reduces physical symptoms, not mental.”
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PropranololMostly positive
“Only 10mg is enough to make me feel comfortable and confident in public speaking.”
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PropranololMostly positive
“I take it together with my adhd meds and it does help to not feel that anxious. And you stay focused and under control.”
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AstaxanthinMostly positive
“Replace the fish oil with krill oil containing naturally occurring astaxanthin. Astaxanthin has been a game changer for me.”
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AstaxanthinMostly positive
“No visible results for me. But it helped to heal the red sunburned skin of my friend.”
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AstaxanthinMostly positive
“The sunburn is *gone*...not a single burn. My skin felt heated and a bit itchy. But there was no burn.”
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AstaxanthinMostly positive
“Astaxanthin is awesome. It's one of my must have supplements. It really helps my eyes, and I have no doubt it's good for the brain.”
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GinkgoMixed
“My fiancé had some pretty bad PSSD similar to what you’ve described, and it’s worked for her.”
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GinkgoMixed
“The rest that I've tried hasn't helped me at all or even made me feel anything, good or bad.”
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GinkgoMixed
“I previously tried ginkgo but I didn't like how I felt after taking it.”
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GinkgoMixed
“I feel great, and my thoughts are fast and verbal fluency is great.”
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Citrulline MalateMostly positive
“Creatin and Citrulline Malate helped me most with reducing PEM, energy shortage, and a general feeling of extreme tiredness.”
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Citrulline MalateMostly positive
“I dropped the citrulline because it was fairly pricey and I couldn't track a real difference.”
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Citrulline MalateMostly positive
“Citrulline malate before workouts and soccer games, I feel a bit light and less sore, but nothing to drive me crazy.”
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Citrulline MalateMostly positive
“I stack Beta-Alanine, Citrulline Malate, and Agmatine ... great focus and energy and the pumps are ridic”
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TudcaMostly positive
“While I do take TUDCA primarily for liver health, anecdotally I've noticed... Slight increase in sense of overall wellbeing.”
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TudcaMostly positive
“I took NAC, taurine, tudca and methylated B vitamins. All these fed and aggravated my hydrogen sulfide overgrowth.”
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TudcaMostly positive
“I went 1g a day in a single dose for a month or two and then that's it... Personally that regimen has helped me cure my fatty liver.”
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TudcaMostly positive
“my bloodwork says otherwise. ... I run tudca too and it works great for me.”
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NSI-189Mixed
“Nsi-189 healed the damage I did to my brain from mdma like nothing else.”
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