PlainPill

NSI-189

People mainly take NSI-189 for mood, focus, memory. Based on 61 first-hand reports. Ranked #123 of 1,974 overall.

49
User score
Mixed
21% positive7% mixed8% negative64% unclear

Of reports that state an outcome, 58% are positive.

Clinical research
Research pending

What NSI-189 does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

Research data for NSI-189 is being compiled.

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

low sublingual doseas reported
1 monthas reported
20mgas reported
10 mg3 weeks

Reported side effects

How often each side effect came up across all reports.

paresthesia ×2attention deficits ×1mania ×1odd pains ×1emotional instability ×1panic attacks ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“NSI literally increase the hippocampus size by 20% confirmed by studies.”
Source discussion ↗
“NSI-189 was funded by DARPA to identify a molecule that would stimulate neurogenesis the most.”
Source discussion ↗
“NSI 189 is something not talked about. That's an actual example of a rarely spoke about nootropic.”
Source discussion ↗
“Expect NSI-189 before GLYX-13, but we also have a couple new products coming within the next few weeks too.”
Source discussion ↗
“NSI-189”
Source discussion ↗
Top discussions (5)

Other options for mood

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate