PlainPill

What people actually say

542 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
IronMostly positive
“I supplemented with sublingual b12 and iron and daily electrolytes and I'm feeling much better.”
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IronMostly positive
“I have noticed quite a few supplements 'especially' herb based Iron supplements not working anymore, when before they used to.”
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IronMostly positive
“Even though that is no where near 200ug, I'm noticing that my fatigue and mood is much better. My skin is clearer, and my period has become slightly less heavy.”
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IronMostly positive
“I had something similar, my issue was low ferritin. I took iron supps and I’m feeling better than I have in years.”
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NAD+Mostly positive
“I use intranasal NAD+ from Alive By Science in the morning, boosts my cognitive function and energy levels noticeably for half the day.”
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NAD+Mostly positive
“running NAD+ throughout the whole thing. I liked this one a lot. Awesome energy all day, months later still feel the improvement.”
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NAD+Mostly positive
“NAD is right away, I feel it instantly and it’s kinda wild how effective it can be.”
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NAD+Mostly positive
“best when combined with NMN but still my favorite. Seems to greatly help with clear thoughts and steady energy.”
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ALAMostly positive
“I also take alcar, alpha lipoic acid, choline, and pqq, but... there is some difference with these, but not as major as with CoQ10.”
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ALAMostly positive
“ALCAR+alpha lipoic acid works as well as Adderall. Actually, it's a bit better for me—it wears off more slowly and doesn't interfere with sleep the way Adderall does.”
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ALAMostly positive
“ALA fixed the issue almost instantly, so I usually don't take ALCAR without the ALA.”
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ALAMostly positive
“R-ALA - has shrunk keloids that I was told would never go away and helped with general over all MS body pain”
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EpitalonMostly positive
“Epitalon: Added this recently at the end of my cycles for the telomere/anti-aging benefits. The unexpected perk? It totally reset my circadian rhythm, amplifying the sleep stack even more.”
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EpitalonMostly positive
“Clearly you need to stack epithalon. I finally slept tho in the morning I feel groggy.”
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EpitalonMostly positive
“after 3-4 days I did feel a definite improvement in energy and mood - more so than with any other peptides I’ve tried.”
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EpitalonMostly positive
“I take 250-500mcg daily. I love it. My sleep has improved— circadian rhythm.”
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“I know pregnenalone helped me with that anxiety... 25mg a day is wonderful.”
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“Now it's like 90% fixed by pregnenolone. However, I been taking around 10 to 20 mg this is the sweet spot for me if I take anymore I get the opposite reaction such as more fatigue and tiredness.”
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“I've been taking pregnenolone, dhea, and tongkhat ali and it helps keep my mind straight while living alone, working alone.”
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“I've never felt more comfortable in my own skin, more calm, or stable. Things just feel right. But: Definitely not a keeper for me. Either no effect or I get more jittery/anxious.”
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SeleniumMostly positive
“I take 200mcg eveyday, but for the first week I took 400mcg. It has exponentially helped my energy levels.”
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SeleniumMostly positive
“even the nootropics that some communities swear by did nothing for me (some that come to mind - racetams, tyrosine/NALT, NAC, methylated B vitamins...”
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SeleniumMostly positive
“200mcg of selenium everyday. Difference when I’m taking it and not taking it is absolutely astounding. Really improved thyroid numbers too.”
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SeleniumMostly positive
“I tried selenium for thyroid support but weirdly it ended up helping way more with energy and overall tiredness.”
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Gotu KolaMostly positive
“It makes me feel very relaxed, and if I take a strong dose I fall asleep within minutes, despite the fact that I normally get insomnia. It also fights anxiety effectively.”
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Gotu KolaMostly positive
“It did help me in the short term but, I don't think that targeting the gabaergic system is a good way to stop anxiety. Anything that targets this system will eventually cause rebound anxiety or dependency.”
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Gotu KolaMostly positive
“I drink gotu kola and vape cbd among other supplements and I think that's what helps with my ADHD the most - this combo gives me a stimulated feeling.”
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Gotu KolaMostly positive
“The gotu kola is similar. I take that before bed when I am on it as well. ... I experience a 'sleep like the dead for, say, 6 hours, then wake up and cannot go back to sleep' effect on Gotu Kola.”
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“Vitamin E is the most effective supplement I've taken for anxiety, depression, lethargy, and anhedonia...even more effective than the SSRI.”
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“Nordic Naturals Ultimate Omega, vitamin e, even the expensive coq10 didn't *really* help my skin.”
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“I can attest to Vitamin E helping the refractory period. But I only took it sporadically.”
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“she told me the only thing that helped was vitamin E. She took it for years... hope this helps with getting more sleep”
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CopperMixed
“Copper was a big savior for me, the difference is huge and started right after starting to focus on it. My deep sleep has only gone up and up.”
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CopperMixed
“I took zinc and copper high dosed and it did not raise my levels. Months now in.”
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CopperMixed
“started supplementing copper, which I believe can be seen on my face since my wrinkles are considerably reduced in size (copper is important for collagen synthesis)”
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CopperMixed
“Heightened taste, smell & hearing. Energy levels skyrocket. My brain feels like it's working more powerfully and efficiently.”
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FastingMostly positive
“on the second day it felt like a very light version of a stimulant. I was super productive and I was grinding my teeth.”
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FastingMostly positive
“I simply did not eat at all that day (so I ate last the night before the vaccination).”
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FastingMostly positive
“I take no food until 17:00. Eat my intake for the day and repeat. I only drink water, coffee, tea though the day. I've been doing this consistently for the past 3 years - no brain fog whatsoever. Energy levels are higher then ever before.”
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FastingMostly positive
“about the 5th day in I started laughing for no reason and just felt more in the moment but it wasn't much and didn't last.”
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