PlainPill

Iron

People mainly take Iron for energy, mood, focus. Based on 131 first-hand reports and 243 meta-analyses & systematic reviews in the medical literature. Ranked #59 of 1,974 overall.

54
User score
Mostly positive
29% positive5% mixed4% negative63% unclear

Of reports that state an outcome, 76% are positive.

Clinical research
AStrong research base
243
meta-analyses
693
RCTs
6,017
papers

What Iron does, according to users

Of the people who reported each effect, the share who said it got better.

What the research says

Systematic reviews and meta-analyses from PubMed, with their published conclusions.

AStrong research base

3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.

PLoS One · 2025 · Meta-analysis / systematic review
Optimal dose and duration of iron supplementation for treating iron deficiency anaemia in children and adolescents: A systematic review and meta-analysis

Conclusion: Low-dose iron supplementation (<5 mg/kg/day) combined with treatment durations of either less than 3 months or more than 6 months, is optimal for improving Hb levels in children and adolescents with IDA. Tailoring treatment based on baseline Hb levels and anaemia severity is essential. These findings provide evidence to support updated guidelines on iron supplementation in paediatric and adolescent populations and inform national anaemia management programmes.

PubMed 39951396 ↗
Neurosci Biobehav Rev · 2025 · Meta-analysis / systematic review
Psychiatric and cognitive outcomes of iron supplementation in non-anemic children, adolescents, and menstruating adults: A meta-analysis and systematic review

Conclusion: Subgroup analyses confirmed consistent results for ID-only groups, youth, and menstruating adults, though supplementation effects were absent when excluding ID participants. This suggests that, before anemia emerges, ID may impact brain function, potentially requiring identification and treatment.

PubMed 40945632 ↗

Dosage people report

As stated by users — not a recommendation. Follow the label or your doctor.

65 mgas reported
dailyas reported
30 mgas reported
every 2-3 monthsas reported
28 mgdaily
low doseas reported

Reported side effects

How often each side effect came up across all reports.

liver accumulation ×1overdose toxicity ×1constipation ×1possible heavy ×1

What users say

Verbatim quotes, shortened only — each links to the original discussion.

“Iron is one of the most common issues, especially for women.”
Source discussion ↗
“I take transdermal magnesium and zinc carnosine and iron usually.”
Source discussion ↗
“Iron 65mg”
Source discussion ↗
“My bloodwork had low iron last two times so my practitioner recommended once a day for now until next bloodwork. I do every 2-3 months.”
Source discussion ↗
“Add Vit B and Iron now. Motsc uses it up.”
Source discussion ↗
Top discussions (5)

Other options for energy

User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate