What people actually say
708 first-hand quotes, shortened but never edited — each links to the original discussion.
AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
GlycineMostly positive
“2 grams with 200mg magnesium before bed gives me crazy good sleep. Crazy vivid dreams.”Source discussion ↗
GlycineMostly positive
“Taking isolated glycine several days in a row makes me super groggy throughout the day. It puts me to sleep almost like a sedative.”Source discussion ↗
GlycineMostly positive
“I take a lot of glycine...I take a couple of teaspoons of the powder every night and it helps me sleep without any sort of payback.”Source discussion ↗
GlycineMostly positive
“I tried using glycine as a sleep aid for a while and it did the opposite. Turns out it's stimulating for some people and sedating for others.”Source discussion ↗
COQ10Mostly positive
“I rely on 200mg of Qunol Co-enzyme Q10 to take with my 40mg of Crestor to prevent statin side effects. Works wonderfully.”Source discussion ↗
COQ10Mostly positive
“even the nootropics that some communities swear by did nothing for me (some that come to mind - racetams, tyrosine/NALT, NAC, methylated B vitamins...”Source discussion ↗
COQ10Mostly positive
“I combined this with NootropicsDepot's Shilajit. Insane energy from this. Such clean mental energy and zero fatigue.”Source discussion ↗
COQ10Mostly positive
“250mg Ubiquinol, 2tsp cod liver oil, and 5g creatine daily... Within about two weeks, I noticed my memory improving.”Source discussion ↗
LGD-4033Mixed
“I've taken LDG-4033 and Ostarine from Ceretropic and noticed slight psychoactive effects from both, immediately (within 30 minutes after dosing).”Source discussion ↗
LGD-4033Mixed
“I did a 10 week LGD cycle, no PCT and I eat a high protein diet... my test was tanked, I could feel it.”Source discussion ↗
LGD-4033Mixed
“I ran 25mg mk677 and 10mg LGD 4033 for 3 months and I gained 9.5kg but my body fat stayed the same.”Source discussion ↗
LGD-4033Mixed
“Overall happy whith the results i like to keep my cycles short 5 weeks and somewhat low dosages even tho the join dryness was really annoyng.”Source discussion ↗
SemaxMostly positive
“The effects have been incredible. It feels like my background distractibility has just vanished. I can lock in and focus even when my phone and other distractions are right next to me.”Source discussion ↗
SemaxMostly positive
“I think Semax actually made my brainfog much worse, or the combo of that and PE-22-28.”Source discussion ↗
SemaxMostly positive
“Ran a cycle of semax for cognition, no changes noted but I feel this one is a long term process.”Source discussion ↗
SemaxMostly positive
“This shit is the shit!! This is what I wish weed and alcohol felt like! I was chill, listened to music, got work done, didn't want to procrastinate. My ahedonia was gone. I hope this shit isn't dangerous because it is awesome.”Source discussion ↗
AniracetamMostly positive
“Aniracetam: Anecdotally I could feel instantaneous mental improvement within 2-3 days... The most significant improvement was attention... organization, and confidence.”Source discussion ↗
AniracetamMostly positive
“This is the first time i've ever taken something that truly has improved my cognitive capacity. My mind has never been so clear.”Source discussion ↗
AniracetamMostly positive
“I just feel more aware of everything. The strongest change is that the music I'm listening to sounds much better.”Source discussion ↗
AniracetamMostly positive
“Overall I would say I improved 60% of my ADHD. Especially while Aniracetam is active in my system.”Source discussion ↗
GHK-CuMostly positive
“Love it. 44 F. Totally helped even out my skin tone (Irish red cheeks), reduced wrinkles on my forehead and neck, thickened my hair which had been thinning, and grew my eye lashes.”Source discussion ↗
GHK-CuMostly positive
“My under-eye hollowness has not disappeared completely, but it has somewhat improved.”Source discussion ↗
GHK-CuMostly positive
“The changes in my hair have been great, the growth rate has accelerated, the texture has improved, and there’s a noticeable shine that wasn’t there before.”Source discussion ↗
GHK-CuMostly positive
“I (60F) inject my test subject 4mg/day. Started at 2mg in January and have seen dramatic changes in overall skin density and texture. Ive lost 96 lbs in 9 months with no loose skin or hair loss.”Source discussion ↗
RetatrutideMostly positive
“Drastically reduced appetite: At 5mg, I experienced near-total suppression of hunger and cravings. Steady, effortless fat loss: I didn't have to track macros obsessively or do extreme cardio.”Source discussion ↗
RetatrutideMostly positive
“I’ve tried Reta and it melted fat away at 1mg - I really disliked the increased heart rate (and it was only 8bpm) and the nuking of my HRV.”Source discussion ↗
RetatrutideMostly positive
“Once I started Reta at 2mg in January, it completely changed my mindset.”Source discussion ↗
RetatrutideMostly positive
“I lost 115 lbs in the last year (260 → 145)...retatrutide seemed to finally address my insulin resistance.”Source discussion ↗
MethylphenidateMixed
“Ritalin/methylphenidate has just been an absolute godsend, a total game-changer. When it kicks in with my morning vape and coffee it is as though my world comes into clear focus.”Source discussion ↗
MethylphenidateMixed
“I take methylphenidate and it’s changed my life for the way way better.”Source discussion ↗
MethylphenidateMixed
“I got diagnosed with ADHD and tried Ritalin and Elvanse and they do help somewhat when I need to learn for an exam but I hate the feeling of being on them.”Source discussion ↗
MethylphenidateMixed
“I was taking Ritalin IR 6x5mg for 2 years and it worked great, I felt motivated, better executive function, better mood.”Source discussion ↗
KratomMixed
“Green or white Kratom powder. My productivity and overall mood have skyrocketed. I dose 4 grams once per day and it’s worked wonders.”Source discussion ↗
KratomMixed
“Kratom/7Hydroxi makes me too sleepy and I feel dumb and slow on it.”Source discussion ↗
KratomMixed
“kratom has been a Godsend and has really helped with getting me back on my feet. My preferred strain is Green Bali and found 2g to be my sweet spot in dose.”Source discussion ↗
KratomMixed
“It keeps the depression, anxiety, suicidal and dark thoughts in check, but it also leaves my attention scattered, confused and makes me feel half-ADHD.”Source discussion ↗
TirzepatideMostly positive
“Tirzepatide works so well! Do some research in the r/peptides subreddit and the r/tirzepatide subreddit. It's the most effective thing I've ever seen for appetite suppressant.”Source discussion ↗
TirzepatideMostly positive
“I’m currently on tirzepatide 7.5mg (midway dose). Stacking sema because tirz isn’t helping it’s serious insomnia and sexual side effects.”Source discussion ↗
TirzepatideMostly positive
“The Tirz was amazing and I dropped to a maintenance dose after I hit 195. When I stopped all peptides for two weeks prior to surgery, the Tirz didnt do anything when I restarted.”Source discussion ↗
TirzepatideMostly positive
“I lost 33 in 4 weeks, 59 in 11 weeks on Tirzep + Test + Deca + Tesa while putting on muscle.”Source discussion ↗