PlainPill

What people actually say

2,057 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
Zinc PicolinateMostly positive
“After 15 mins or so, I experienced these effects: Warm body temperature, Heightened self-esteem, Dulling of emotions... Only bad thing is I feel slightly dumber.”
Source discussion ↗
Zinc PicolinateMostly positive
“After taking it I feel slightly better, whether it's placebo or I had zinc deficiency is irrelevant to me.”
Source discussion ↗
Zinc PicolinateMostly positive
“Mine stopped a few days after I added zinc picolate. I take them at different times of the day.”
Source discussion ↗
Zinc PicolinateMostly positive
“Zinc picolinate - I’m zinc deficient and a lot of individuals with adhd have zinc deficiencies ... This helps with attention as well as immunity.”
Source discussion ↗
CognanceMostly positive
“i swear to god cognance (i stack with saffron) helped me cope with my anxiety and ocd in a way no prescription med ever has.”
Source discussion ↗
CognanceMostly positive
“I've been taking it for about two weeks now with no noticeable results... but my experience has been the opposite. It has consistently for the past 3 weeks had a significant effect on my stress, anxiety and wellbeing.”
Source discussion ↗
CognanceMostly positive
“so far cognance has really helped with anxiety significantly... The past 3 nights I have only woken up once or twice.”
Source discussion ↗
CognanceMostly positive
“I use cognance and it seems to have helped my focus and anxiety.”
Source discussion ↗
“With taking the oil my pain reduced within 30 minutes to the point where I have not found it necessary to take any painkillers yet.”
Source discussion ↗
“When I started cooking with it I noticed an immediate increase in alertness and so on.”
Source discussion ↗
“I personally never noticed any effect from 1-2 tbsp of coconut oil.”
Source discussion ↗
“I also took coconut oil which has been said to help combat viruses and candida. Although I did feel better someone a lot of my symptoms still remained.”
Source discussion ↗
“maca root majorly helped my anxiety, and is giving me the confidence I need to actively improve my life.”
Source discussion ↗
“Over time I tried gelatinized maca root (amazing result, but concerning side effect, see below)”
Source discussion ↗
“Maca Root, got recommend as a natural energy supplement for workouts. What I didn't know...is that it is also natural Viagra.”
Source discussion ↗
“I take 6 grams daily for maintenance...really realized my anxiety was preventing me from sleeping once I tried maca & the anxiety melted away.”
Source discussion ↗
L-DopaMixed
“I find 4-hydroxyphenylalanine and L-γ-glutamylethylamide make a huge difference in keeping myself on an even keel..”
Source discussion ↗
L-DopaMixed
“L-Dopa is making me a bit anxious but sure helps me with depression and focus.”
Source discussion ↗
L-DopaMixed
“I have been taking L-Dopa and it has been working for me. My moods have been consistent and my anxiety have been almost non-existent.”
Source discussion ↗
L-DopaMixed
“I've taken both L-Dopa and 5-HTP before and they didn't do shit.”
Source discussion ↗
SarcosineMostly positive
“sarcosine + NAC nailed it. I literally cannot tell the difference. I feel so amazing.”
Source discussion ↗
SarcosineMostly positive
“long courses of Sarcosine (daily for a month+ at a time) helped tremendously and permanently, however when I tried it again more recently it triggered anxiety and overthinking.”
Source discussion ↗
SarcosineMostly positive
“GlyT1 Inhibitors: Sarcosine and (lesser extent) dimethylglycine cause glycine reuptake inhibition, proven quite effective for anxiety ... Helps me a lot.”
Source discussion ↗
SarcosineMostly positive
“2000mg sarcosine helps with the emotional blunting often seen in schizophrenia, and it aids cognitive performance through enhanced NMDA signaling. I have taken both for a few weeks and they have helped me tremendously.”
Source discussion ↗
Resistance TrainingMostly positive
“more weight training. I was pumping iron, but not often enough so I lost more muscle mass than what I needed to.”
Source discussion ↗
Resistance TrainingMostly positive
“I find resistance training especially effective. Quads, glutei, calves, triceps, biceps, shoulders, abs - get them all reasonable sore, and you crash like a baby.”
Source discussion ↗
Resistance TrainingMostly positive
“I made incredible strides and even worked through the right shoulder issue that had been hampering me for years.”
Source discussion ↗
Resistance TrainingMostly positive
“my hack to get it up without pharmaceuticals and have increased libido. Is doing lots of squats with weights”
Source discussion ↗
DihexaMostly positive
“The effects have been promising, because I found myself not only better in actual routine work, but also studying and learning, which was really hard to me before. It felt like combining mental clarity with neural plasticity.”
Source discussion ↗
DihexaMostly positive
“I've taken it three times, all orally. It's easily the most profound substance i've tried yet...Better memory and general retention, greater plasticity...improved physical performance”
Source discussion ↗
DihexaMostly positive
“fish oil psilocybin dihexa and fast for at least 24 hrs once per week... these are the things i feel were absolutely critical in my recovery.”
Source discussion ↗
DihexaMostly positive
“some peptides like dihexa, Cerebrolysin, selank, semax, and Retatrutide also helped my recovery”
Source discussion ↗
“I really got better from anxiety ... on effexor. My personal miracle drug does not work for everyone.”
Source discussion ↗
“I tried Venlafaxine and my ADHD improved significantly. However, it also had a certain amount of excitotoxicity, and I couldn't sleep at night.”
Source discussion ↗
“I started Venlafaxine three months ago when I got depressed again...and it got me out of bed, but NAC was the game changer for me.”
Source discussion ↗
“I found that Venlafaxine was good once it down regulated my norephineprine. Before I was constantly full of somatic anxiety but now it’s definitely improved.”
Source discussion ↗
“took the tribulus, and 30 minutes later I jumped out of bed with a massive amount of energy and drive to go do stuff.”
Source discussion ↗
“List of things I've tried (some worked, but only for a few days and then never worked again)”
Source discussion ↗
“ND Trib/Now Trib did gave me sides over time : worse sleep , frequent pee urge ( i guess irritated prostate/bladder from higher dht )”
Source discussion ↗
“I also started trying the ND Tribulus and it gives me extra physical energy, but a sort of aggressive energy.”
Source discussion ↗
User reports — what people say about supplements — PlainPill