PlainPill

What people actually say

2,057 first-hand quotes, shortened but never edited — each links to the original discussion.

AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
“I woke up the next day feeling incredible! I felt light and buoyant...I felt light and buoyant. I had a strong desire to be outside in nature...my memory started to improve, my verbal fluency went up as well.”
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“Used memantine to get off of kratom and it worked amazingly! But now I’m dependent on memantine.”
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“I really like Memantine and Agmatine. Both works effective in terms of treating my anxiety and anhedonia. Unfortunately they both create too many side-effects. Memantine makes euphoric and wierd.”
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NiacinMostly positive
“If you over methylate, niacin may also help you. Binds to free methyl groups... It's how I fixed my heart palpitations after taking methylsulfonymethan.”
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NiacinMostly positive
“Been taking Niacin, but other than the flush, I've found it makes me feel kinda irritable after taking it and my stomach doesn't feel great.”
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NiacinMostly positive
“I take niacin daily and have noticed big improvements in mental clarity / focus.”
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NiacinMostly positive
“Had bad flushing w/ the niacin. Felt like I was on fire, massive blotching covered entire body.”
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“Ephedrine gives me tons of energy, makes me happy, positive, and talkative. It's an excellent pre-workout, though it doesn't suppress my appetite like it's supposed.”
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“This morning I had about 200mg of caffeine with ephedrine pre-workout because I didnt get the best sleep last night. I could not focus at ALL today at work.”
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“with 100mg caffeine, 200mg theanine, and 25mg ephedrine I still get pretty jittery. I've been taking 25 mg Ephedrine, 200 caffeine, 450 suntheanine, and 325 aspirin (not as a nootropic, to promote fat loss). Works pretty well for me.”
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“closest thing to adderall is ephedrine. I current switched from the ECA stack to the ECY stack (ephedrine, caffeine, Yohimbine) and it's working better for me.”
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“I also added Tesamorelin 2 months in due to the harder time sleeping on Retatrutide and wanting to accelerate the burn of my visceral fats (2mg 5x a week). Worked like magic for me.”
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“I now have my tesa early morning still fasted from Monday to Friday. My Reta Friday mornings as well. No tesa or Reta on weekends, and found my sleep improved dramatically.”
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“Did a quick Reta run, then slowed that down and started the GH journey. And it has been great. I feel a lot stronger and my endurance has boosted!”
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“I did an eight week cycle of tesamorelin 2mg/day on week days, weekends off, and it went really well. I definitely lost fat, gained muscle, and I look and feel a ton healthier.”
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TadalafilMostly positive
“After a week of 2.5 mg twice a day, this is my favourite drug ever. My brain fog has gone...My mood is so much better, similar to an SSRI but without the flat feeling.”
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TadalafilMostly positive
“I use it sporadically as a preworkout, 5mg before gym, gets a nice pump going - I always get a stuffy nose and that's about it from side effects that Ive noticed.”
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TadalafilMostly positive
“It's probably the only drug I've ever taken that's improved my overall mood and impacted my mental health positively. People say it's because the improved blood flow in the brain.”
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TadalafilMostly positive
“I take it for neuropathy. It’s solved about 95% of the tingling... Also fixed ED. I’m cutting the pills in half so it’s 2.5mg a day but works wonders.”
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IronMostly positive
“I supplemented with sublingual b12 and iron and daily electrolytes and I'm feeling much better.”
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IronMostly positive
“I have noticed quite a few supplements 'especially' herb based Iron supplements not working anymore, when before they used to.”
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IronMostly positive
“Even though that is no where near 200ug, I'm noticing that my fatigue and mood is much better. My skin is clearer, and my period has become slightly less heavy.”
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IronMostly positive
“I had something similar, my issue was low ferritin. I took iron supps and I’m feeling better than I have in years.”
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PolygalaMostly positive
“I also take 100mg of Polygala 3x a day sublingual. It helps with recurring bad thoughts, and focus...helps with overall mood and sleep.”
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PolygalaMostly positive
“I’ve found Polygala was much better for focus whereas agmatine was way better for my mood.”
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PolygalaMostly positive
“Polygala alone (for me): quieter mind, slightly clearer thinking, but also slightly 'flattened' feeling...but in this combo it suddenly feels like the foundation that makes everything else work better.”
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PolygalaMostly positive
“It immediately rid me of depression/anhedonia. My focus, energy, and memory all seem to have improved...I feel like the best version of myself.”
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“I know pregnenalone helped me with that anxiety... 25mg a day is wonderful.”
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“Now it's like 90% fixed by pregnenolone. However, I been taking around 10 to 20 mg this is the sweet spot for me if I take anymore I get the opposite reaction such as more fatigue and tiredness.”
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“I've been taking pregnenolone, dhea, and tongkhat ali and it helps keep my mind straight while living alone, working alone.”
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“I've never felt more comfortable in my own skin, more calm, or stable. Things just feel right. But: Definitely not a keeper for me. Either no effect or I get more jittery/anxious.”
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EpitalonMostly positive
“Epitalon: Added this recently at the end of my cycles for the telomere/anti-aging benefits. The unexpected perk? It totally reset my circadian rhythm, amplifying the sleep stack even more.”
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EpitalonMostly positive
“Clearly you need to stack epithalon. I finally slept tho in the morning I feel groggy.”
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EpitalonMostly positive
“after 3-4 days I did feel a definite improvement in energy and mood - more so than with any other peptides I’ve tried.”
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EpitalonMostly positive
“I take 250-500mcg daily. I love it. My sleep has improved— circadian rhythm.”
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SabroxyMostly positive
“Sabroxy: Poor man's Ritalin, and cleaner feeling in my experience. Dopamine agonist. I take it once in a while if I need to be laser focused and awake.”
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SabroxyMostly positive
“I tested Sabroxy for quite some time now and found it very consistent in giving me brain fog and an overwhelmed feeling of demotivation.”
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SabroxyMostly positive
“Combined with caffeine and sabroxy, there was a notable improvement in my attention span and overall mood.”
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SabroxyMostly positive
“sabroxy is weaker but very pleasant and doesn't have any side effects I have noticed. Nice energy and mental focus boost.”
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KannaMostly positive
“Kanna tablets. Dissolve under the tongue...I can't sing Kannas praises enough. It's the instant cure for my brain fog, lack of energy, and lack of motivation.”
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User reports — what people say about supplements — PlainPill