Best for heart & lipids

64 options people report for cholesterol, blood pressure, HRV, ranked by the share of users who say it improved — weighted by how many reports there are.

Weight loss Appetite Focus Energy Sleep Anxiety Mood Memory Performance Recovery Pain & inflammation Digestion Libido Hormones Blood sugar Heart & lipids Skin & hair Immunity Longevity

Type:All Supplements Peptides Medications Substances Lifestyle SARMs OtherResearch-backed only

46 results

151

Omega-3Supplement

Mood Focus Anxiety

77% report better Heart & lipids

31 reports

Mostly positiveAResearch: Strong

277

Psyllium HuskSupplement

Digestion Heart & lipids Appetite

100% report better Heart & lipids

10 reports

Mostly positiveAResearch: Strong

351

TaurineSupplement

Anxiety Sleep Mood

100% report better Heart & lipids

9 reports

Mostly positiveAResearch: Strong

454

MagnesiumSupplement

Sleep Anxiety Mood

90% report better Heart & lipids

10 reports

Mostly positiveAResearch: Strong

550

BerberineSupplement

Blood sugar Weight loss Energy

89% report better Heart & lipids

9 reports

MixedAResearch: Strong

641

Vitamin K2Supplement

Mood Energy Heart & lipids

100% report better Heart & lipids

5 reports

Mostly positiveAResearch: Strong

760

L-CitrullineSupplement

Libido Performance Heart & lipids

86% report better Heart & lipids

7 reports

Mostly positiveAResearch: Strong

873

RetatrutidePeptide

Weight loss Energy Appetite

75% report better Heart & lipids

8 reports

Mostly positiveBResearch: Moderate

970

TirzepatideMedication

Weight loss Appetite Mood

83% report better Heart & lipids

6 reports

Mostly positiveAResearch: Strong

1035

GarlicSupplement

Heart & lipids Immunity Libido

83% report better Heart & lipids

6 reports

Mostly positiveAResearch: Strong

1157

CialisMedication

Libido Performance Heart & lipids

100% report better Heart & lipids

4 reports

Mostly positiveBResearch: Moderate

1251

CitrullineSupplement

Performance Heart & lipids Libido

100% report better Heart & lipids

4 reports

Mostly positiveAResearch: Strong

1323

StatinsMedication

Heart & lipids Blood sugar

100% report better Heart & lipids

4 reports

MixedAResearch: Strong

1452

Vitamin DSupplement

Mood Energy Sleep

58% report better Heart & lipids

12 reports

Mostly positiveAResearch: Strong

1562

Magnesium CitrateSupplement

Sleep Anxiety Digestion

100% report better Heart & lipids

3 reports

Mostly positiveAResearch: Strong

1662

TadalafilMedication

Libido Performance Mood

100% report better Heart & lipids

3 reports

Mostly positiveAResearch: Strong

1751

NACSupplement

Mood Anxiety Focus

100% report better Heart & lipids

3 reports

MixedAResearch: Strong

1850

Ginkgo BilobaSupplement

Focus Memory Libido

100% report better Heart & lipids

3 reports

Mostly positiveAResearch: Strong

1945

L-ArginineSupplement

Libido Heart & lipids Anxiety

100% report better Heart & lipids

3 reports

MixedAResearch: Strong

2038

ResveratrolSupplement

Longevity Performance Heart & lipids

100% report better Heart & lipids

3 reports

MixedAResearch: Strong

2123

NattokinaseSupplement

Heart & lipids Immunity Libido

100% report better Heart & lipids

3 reports

Mostly positiveBResearch: Moderate

2257

L-TheanineSupplement

Anxiety Focus Sleep

75% report better Heart & lipids

4 reports

Mostly positiveAResearch: Strong

2340

PotassiumSupplement

Energy Anxiety Heart & lipids

75% report better Heart & lipids

4 reports

Mostly positiveAResearch: Strong

2456

CreatineSupplement

Performance Focus Energy

100% report better Heart & lipids

2 reports

Mostly positiveAResearch: Strong

2548

PycnogenolSupplement

Focus Libido Heart & lipids

100% report better Heart & lipids

2 reports

Mostly positiveAResearch: Strong

2647

NiacinSupplement

Mood Energy Focus

100% report better Heart & lipids

2 reports

Mostly positiveAResearch: Strong

2746

NMNSupplement

Energy Performance Sleep

100% report better Heart & lipids

2 reports

MixedAResearch: Strong

2844

Citrulline MalateSupplement

Performance Recovery Heart & lipids

100% report better Heart & lipids

2 reports

Mostly positiveAResearch: Strong

2940

COQ10Supplement

Energy Focus Mood

100% report better Heart & lipids

2 reports

Mostly positiveAResearch: Strong

3032

CurcuminSupplement

Pain & inflammation Mood Anxiety

100% report better Heart & lipids

2 reports

MixedAResearch: Strong

3126

Potassium CitrateSupplement

Heart & lipids Mood Energy

100% report better Heart & lipids

2 reports

MixedAResearch: Strong

3251

PiracetamSupplement

Focus Memory Mood

67% report better Heart & lipids

3 reports

MixedAResearch: Strong

3350

AshwagandhaSupplement

Anxiety Mood Sleep

67% report better Heart & lipids

3 reports

MixedAResearch: Strong

3447

Vitamin CSupplement

Energy Skin & hair Immunity

67% report better Heart & lipids

3 reports

Mostly positiveAResearch: Strong

3529

BeetrootSupplement

Performance Libido Heart & lipids

67% report better Heart & lipids

3 reports

Mostly positiveAResearch: Strong

3626

AspirinMedication

Focus Heart & lipids Pain & inflammation

67% report better Heart & lipids

3 reports

MixedAResearch: Strong

3755

Rhodiola RoseaSupplement

Energy Mood Anxiety

50% report better Heart & lipids

2 reports

Mostly positiveAResearch: Strong

3847

Alpha-GpcSupplement

Focus Mood Energy

50% report better Heart & lipids

2 reports

MixedBResearch: Moderate

3936

KetamineMedication

Mood Anxiety Heart & lipids

50% report better Heart & lipids

2 reports

MixedAResearch: Strong

4018

RapamycinMedication

Recovery Heart & lipids Immunity

50% report better Heart & lipids

2 reports

MixedAResearch: Strong

4138

BupropionMedication

Mood Energy Focus

33% report better Heart & lipids

3 reports

MixedAResearch: Strong

4252

CaffeineSubstance

Energy Focus Anxiety

0% report better Heart & lipids

4 reports

MixedAResearch: Strong

4346

NicotineSubstance

Focus Energy Mood

0% report better Heart & lipids

3 reports

MixedAResearch: Strong

4446

ModafinilMedication

Focus Energy Mood

0% report better Heart & lipids

2 reports

MixedAResearch: Strong

4525

THCSubstance

Anxiety Sleep Memory

0% report better Heart & lipids

2 reports

MixedAResearch: Strong

4623

MarijuanaSubstance

Sleep Focus Memory

0% report better Heart & lipids

2 reports

MixedAResearch: Strong

Minimum 2 reports per entry. Information only — not medical advice. How rankings work