People mainly take Potassium Citrate for heart & lipids, mood, energy. Based on 11 first-hand reports and 13 meta-analyses & systematic reviews in the medical literature. Ranked #524 of 1,974 overall.
Of reports that state an outcome, 57% are positive.
Of the people who reported each effect, the share who said it got better.
Systematic reviews and meta-analyses from PubMed, with their published conclusions.
3+ meta-analyses or systematic reviews and 10+ randomized controlled trials in humans. The grade measures how much human research exists — read the conclusions below for what it found.
Conclusion: Because of the rarity of the disease and the poor level of evidence in the literature, these statements could not be graded. This clinical practice recommendation provides guidance on all aspects of the management of both adults and children with cystinuria, including diagnosis, surgery, and medical treatment.
PubMed 32918941 ↗Conclusion: Citrate salts prevent new stone formation and reduce further stone growth in patients with residual stones that predominantly contain oxalate. The quality of reported literature remains moderate to poor; hence a well-designed statistically powered multi-centre RCT is needed in order to answer relevant questions concerning the efficacy of citrate salts.
PubMed 26439475 ↗Conclusion: The available evidence shows that citrate supplement effectively reduces the recurrence of nephrolithiasis in patients undergoing SWL. However, statistical analysis of a larger trial conducted with methodological rigor is warranted.
PubMed 27915395 ↗Conclusion: Our review indicates that further larger scale trials are required to analyze whether non-pharmacological interventions can increase urinary citrate levels and act in kidney stone prevention.
PubMed 26311217 ↗As stated by users — not a recommendation. Follow the label or your doctor.
How often each side effect came up across all reports.
Verbatim quotes, shortened only — each links to the original discussion.
“I take potassium citrate when I think of it. I never exceed 1/4 tsp”
“after a long ride my legs gave out and I had wicked charlie horses so I started supplementing with Potassium Citrate especially when I go for long rides”
“Getting 3-4g potassium daily is very beneficial—I personally use potassium citrate supplementation”
“soluble potassium citrate is fine”
“I've been taking potassium citrate (powder) 1/4 teaspoon in two cups of water for years...taking too much can be very dangerous and by dangerous I mean fatal.”
User data from public discussions; research from PubMed. Information only, not medical advice — talk to a doctor before starting, stopping or combining anything. Data updated October 2, 2026. How we rate