PlainPill

Saffron vs Vitamin D for mood

Short answer: For mood, users rate them about the same: 92% report improvement with Saffron (123 reports) and 88% with Vitamin D (308 reports).

Saffron has 88 meta-analyses and 119 randomized trials on PubMed; Vitamin D has 3,251 and 4,560.

Based on 323 reports about Saffron and 2,323 about Vitamin D. Not medical advice.

Saffron
Supplement
Vitamin D
Supplement
User score5848
Verdict
Mostly positive
Mostly positive
Positive
of reports that state an outcome
64%65%
Reports3232,323
ResearchAResearch: StrongAResearch: Strong
Meta-analyses / RCTs88 / 1193,251 / 4,560
Mainly used for
Weight loss
% reporting improvement
—62% (8)
Appetite
% reporting improvement
80% (10)67% (3)
Focus
% reporting improvement
80% (30)82% (55)
Energy
% reporting improvement
78% (18)87% (215)
Sleep
% reporting improvement
77% (13)50% (105)
Anxiety
% reporting improvement
80% (75)65% (82)
Mood
% reporting improvement
92% (123)88% (308)
Memory
% reporting improvement
50% (2)83% (12)
Performance
% reporting improvement
—100% (23)
Recovery
% reporting improvement
—91% (11)
Pain & inflammation
% reporting improvement
100% (3)73% (30)
Digestion
% reporting improvement
50% (2)50% (14)
Libido
% reporting improvement
75% (12)80% (45)
Hormones
% reporting improvement
—87% (55)
Blood sugar
% reporting improvement
—100% (2)
Heart & lipids
% reporting improvement
50% (2)60% (15)
Skin & hair
% reporting improvement
—89% (28)
Immunity
% reporting improvement
—99% (74)
Longevity
% reporting improvement
—78% (9)
Common side effectsheadache, anxiety, appetite suppression, vivid dreamsinsomnia, anxiety, fatigue, hypercalcemia
Typical dose reporteddaily, morningdaily
Saffron
Latest review conclusion

Saffron demonstrates promise in improving ADHD symptoms, with an acceptable safety profile. Future well-designed multicentral studies are suggested.

J Atten Disord, 2024 ↗
What a user said
“I just sneak some into whatever soup we are having. I honestly think it has made a huge difference.”
Full Saffron profile →
Vitamin D
Latest review conclusion

These results indicate that the prevalence of vitamin D deficiency was more elevated in obese subjects. The vitamin D deficiency was associated with obesity irrespective of age, latitude, cut-offs to define vitamin D deficiency and the Human Development Index of the study location.

Obes Rev, 2015 ↗
What a user said
“First thing I noticed was my mood & libido, I have more 'feeling/sensitivity' down there.”
Full Vitamin D profile →

Related comparisons

Percentages come from first-hand user reports and are not clinical outcomes. Talk to a doctor before starting, stopping or combining anything. How we rate