What people actually say
975 first-hand quotes, shortened but never edited — each links to the original discussion.
AllWeight lossAppetiteFocusEnergySleepAnxietyMoodMemoryPerformanceRecoveryPain & inflammationDigestionLibidoHormonesBlood sugarHeart & lipidsSkin & hairImmunityLongevity
Black Seed OilMostly positive
“Black seed yes. I'm taking capsules of both strengths. I was hoping it would help with exczema/skin health. But so far it's mainly good for immunity, anxiety. Good all rounder but not sure I'll get it again.”Source discussion ↗
Black Seed OilMostly positive
“1.5 tsp a day and I'm finally enjoying music,video games and feel a genuine appreciation for being alive.”Source discussion ↗
Black Seed OilMostly positive
“i've tried CBD oil, black seed oil and NAC to help with the glutamate / gaba imbalance but I can't say any of these have significantly made my symptoms better.”Source discussion ↗
Black Seed OilMostly positive
“I started taking BSO a few days ago and I’m blown away, my anxiety, depression, muscle aches, etc. have all improved significantly.”Source discussion ↗
Intermittent FastingMostly positive
“I would suggest trying Intermittent fasting. I have much better focus and clarity.”Source discussion ↗
Intermittent FastingMostly positive
“When I did intermittent fasting I got along OK and feel good if I drink enough water.”Source discussion ↗
Intermittent FastingMostly positive
“I also did intermittent fasting for the first 4 months and lost my first 50 lbs that way.”Source discussion ↗
Intermittent FastingMostly positive
“Have you tried intermittent fasting? That cleared up my brain fog when a lot of other things didn't help.”Source discussion ↗
ResveratrolMixed
“started NMN and resveratrol which I can definitely feel a difference and see the sleep has gotten better since.”Source discussion ↗
ResveratrolMixed
“I feel more tired in my body, but mentally sharper. I am quite in tune to my blood sugar levels and it feels like they have dropped.”Source discussion ↗
ResveratrolMixed
“I've heard lots of horror stories about side effects of resveratrol, and it has such a complicated mechanism of action.”Source discussion ↗
ResveratrolMixed
“For me nadh, resveratrol and shilajit (sometimes with coq10) is my unbeatable energy stack.”Source discussion ↗
MemantineMixed
“I feel like I have all the positives of Adderall (focus, motivation, mood increase) without any noticeable downsides. No crash, no anxiety, no cardiac issues.”Source discussion ↗
MemantineMixed
“I woke up the next day feeling incredible! I felt light and buoyant...I felt light and buoyant. I had a strong desire to be outside in nature...my memory started to improve, my verbal fluency went up as well.”Source discussion ↗
MemantineMixed
“Used memantine to get off of kratom and it worked amazingly! But now I’m dependent on memantine.”Source discussion ↗
MemantineMixed
“I really like Memantine and Agmatine. Both works effective in terms of treating my anxiety and anhedonia. Unfortunately they both create too many side-effects. Memantine makes euphoric and wierd.”Source discussion ↗
NiacinMostly positive
“If you over methylate, niacin may also help you. Binds to free methyl groups... It's how I fixed my heart palpitations after taking methylsulfonymethan.”Source discussion ↗
NiacinMostly positive
“Been taking Niacin, but other than the flush, I've found it makes me feel kinda irritable after taking it and my stomach doesn't feel great.”Source discussion ↗
NiacinMostly positive
“I take niacin daily and have noticed big improvements in mental clarity / focus.”Source discussion ↗
NiacinMostly positive
“Had bad flushing w/ the niacin. Felt like I was on fire, massive blotching covered entire body.”Source discussion ↗
TesamorelinMixed
“I also added Tesamorelin 2 months in due to the harder time sleeping on Retatrutide and wanting to accelerate the burn of my visceral fats (2mg 5x a week). Worked like magic for me.”Source discussion ↗
TesamorelinMixed
“I now have my tesa early morning still fasted from Monday to Friday. My Reta Friday mornings as well. No tesa or Reta on weekends, and found my sleep improved dramatically.”Source discussion ↗
TesamorelinMixed
“Did a quick Reta run, then slowed that down and started the GH journey. And it has been great. I feel a lot stronger and my endurance has boosted!”Source discussion ↗
TesamorelinMixed
“I did an eight week cycle of tesamorelin 2mg/day on week days, weekends off, and it went really well. I definitely lost fat, gained muscle, and I look and feel a ton healthier.”Source discussion ↗
TadalafilMostly positive
“After a week of 2.5 mg twice a day, this is my favourite drug ever. My brain fog has gone...My mood is so much better, similar to an SSRI but without the flat feeling.”Source discussion ↗
TadalafilMostly positive
“I use it sporadically as a preworkout, 5mg before gym, gets a nice pump going - I always get a stuffy nose and that's about it from side effects that Ive noticed.”Source discussion ↗
TadalafilMostly positive
“It's probably the only drug I've ever taken that's improved my overall mood and impacted my mental health positively. People say it's because the improved blood flow in the brain.”Source discussion ↗
TadalafilMostly positive
“I take it for neuropathy. It’s solved about 95% of the tingling... Also fixed ED. I’m cutting the pills in half so it’s 2.5mg a day but works wonders.”Source discussion ↗
IronMostly positive
“I supplemented with sublingual b12 and iron and daily electrolytes and I'm feeling much better.”Source discussion ↗
IronMostly positive
“I have noticed quite a few supplements 'especially' herb based Iron supplements not working anymore, when before they used to.”Source discussion ↗
IronMostly positive
“Even though that is no where near 200ug, I'm noticing that my fatigue and mood is much better. My skin is clearer, and my period has become slightly less heavy.”Source discussion ↗
IronMostly positive
“I had something similar, my issue was low ferritin. I took iron supps and I’m feeling better than I have in years.”Source discussion ↗
Milk ThistleMostly positive
“Adrafinil and milk thistle is my current best solution...Milk thistle helps for the hepatoxicity (as you know)”Source discussion ↗
Milk ThistleMostly positive
“Nothing much happened. I still had those problems after trying all that nootropics and supplements.”Source discussion ↗
Milk ThistleMostly positive
“Milk thistle can with some people cause Hypothyroidism... I had to quit taking I started gaining weight and my thyroid was swollen and hurt.”Source discussion ↗
Milk ThistleMostly positive
“I have improved taking milk thistle which helps my liver heal and to detoxify toxins.”Source discussion ↗
PregnenoloneMixed
“I know pregnenalone helped me with that anxiety... 25mg a day is wonderful.”Source discussion ↗
PregnenoloneMixed
“Now it's like 90% fixed by pregnenolone. However, I been taking around 10 to 20 mg this is the sweet spot for me if I take anymore I get the opposite reaction such as more fatigue and tiredness.”Source discussion ↗
PregnenoloneMixed
“I've been taking pregnenolone, dhea, and tongkhat ali and it helps keep my mind straight while living alone, working alone.”Source discussion ↗
PregnenoloneMixed
“I've never felt more comfortable in my own skin, more calm, or stable. Things just feel right. But: Definitely not a keeper for me. Either no effect or I get more jittery/anxious.”Source discussion ↗